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  1. A Study of New Tools for the Clinical Assessment and Rehabilitation of Concussion

    Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and ...

  2. Common Mechanisms of Anti-Suicidal Drug Action - Mayo Clinic

    The purpose of this study is to characterize the effects of clozapine, lithium, and ketamine on mTOR signaling, glucose uptake, and overall cellular metabolic ...

  3. A Study Comparing the Long Term Safety of Entyvio (Vedolizumab) to Other Biologic Agents in Patients with Ulcerative Colitis or Crohn's Disease - Mayo Clinic

    The purpose of this study is to assess the long-term safety of vedolizumab versus other biologic agents in participants with Ulcerative Colitis or Crohn's ...

  4. Reporting of Side Effects Among Stage III and IV Melanoma Patients Treated with Immune Checkpoint Inhibitors - Mayo Clinic

    Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and ...

  5. Patient Reported Outcomes inVestigation Following Initiation of Drug Therapy With Entresto (Sacubitril/Valsartan) in Heart Failure - Mayo Clinic

    About this study. Real-world evidence of the clinical course of patient symptoms following initiation of sacubitril/valsartan via PROs with a ...

  6. The Fourth Left Atrial Appendage Occlusion Study (LAAOS-4) - Mayo Clinic

    The purpose of this study is to determine if catheter-based endovascular left atrial appendage occlusion prevents ischemic stroke or systemic embolism in ...

  7. A Study to Evaluate the Epidemiology of Estrogen Genotoxicity in Breast Cancer - Mayo Clinic

    About this study. The purpose of this study is to recruit 2000 incident cases of primary breast cancer in order to perform laboratory assays to measure ...

  8. Study in Pediatrics with HypEREosinophilic Syndrome - Mayo Clinic

    The purpose of this study is to investigate the effectiveness and safety of mepolizumab in children and adolescents with hypereosinophilic syndrome (HES) who ...

  9. Dissecting the Genetic Environment Contributions of Autoimmune Liver Disease - Mayo Clinic

    About this study. The overall objective of this proposal is to conduct a systematic approach to dissect both genetic underpinnings and non-genetic factors ...

  10. Descriptive Analysis of Gut Microbiome Alterations in Hyperoxaluric Patients - Mayo Clinic

    About this study. To characterize the microbiome in 4 groups of subjects (primary hyperoxaluria type I (PH1), idiopathic CaOx stone, enteric hyperoxaluria ...