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  1. A Study to Characterize Functional Biomarkers of Systemic Lupus Erythematosus (SLE) - Mayo Clinic

    The purpose of this study is to investigate syndecan-1 expression levels on immune cells, especially pDCs, in systemic lupus erythematosus (SLE) patients by ...

  2. Wilms Tumor Clinical Trials - Mayo Clinic Research

    This phase III clinical trial is studying how well combination chemotherapy and surgery work in treating young patients with Bilateral Wilms tumor and children ...

  3. Projects - Brain Adaptation and Stimulation: Brian N. Lundstrom - Mayo Clinic Research

    Projects · Multiscale EEG/magnetoencephalography (MEG) biomarkers. Epilepsy is characterized by paroxysmal and sometimes infrequent ictal events termed seizures.

  4. Effect of Tirzepatide on Physical Function in Postmenopausal Women With Obesity - Mayo Clinic

    About this study. In postmenopausal women, obesity increases the risk of physical function decline and premature aging, thus increasing the risk of vascular ...

  5. A Study of AdAPT-001 in Subjects With Sarcoma and Refractory Solid Tumors - Mayo Clinic

    The purpose of this study is to determine the safety and tolerability profile of a single dose of AdAPT-001 in subjects with advanced solid tumors that have ...

  6. Doxorubicin and Cyclophosphamide Followed By Trastuzumab, Paclitaxel, and Lapatinib in Treating Patients With Early-Stage HER2-Positive Breast Cancer That Has Been Removed By Surgery - Mayo Clinic

    RATIONALE: Drugs used in chemotherapy, such as doxorubicin, cyclophosphamide, and paclitaxel, work in different ways to stop the growth of tumor cells, either ...

  7. Study of Selective BRAF Kinase Inhibitor Dabrafenib Monotherapy Twice Daily and in Combination with Dabrafenib Twice Daily and Trametinib Once Daily in Combination Therapy in Subjects With BRAF V600E Mutation Positive Metastatic (Stage IV) Non-small Cell Lung Cancer - Mayo Clinic

    Subjects will receive dabrafenib 150 mg twice daily (BID) in monotherapy treatment and dabrafenib 150 mg bid and trametinib 2 mg once daily in combination ...

  8. A Study to Evaluate the Safety, Pharmacokinetics, and Efficacy of Isatuximab in Patients With Multiple Myeloma - Mayo Clinic

    About this study. Primary Objective: - Part A: To evaluate the safety of SAR650984 (isatuximab) in patients with relapsed/refractory multiple myeloma (RRMM) ...

  9. A Study of the Use of the Hansen Medical System in Patients with Paroxysmal Atrial Fibrillation - Mayo Clinic

    The purpose of this study is to assess the safety and performance of the Hansen Medical Sensei Robotic System and Artisan Catheter when used to robotically ...

  10. A Study of Colesevelam in Fecal Incontinence - Mayo Clinic

    The purpose of this study is to compare the effects of a combination of colesevelam and clonidine to a placebo on bowel symptoms in patients with urge or ...