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  1. A Study to Examine the Safety, Tolerability and Effects on Abnormal Bone Formation of REGN2477 in Patients With Fibrodysplasia Ossificans Progressiva - Mayo Clinic

    About this study. This is a two period study design consisting of a 6-month, randomized, double-blind placebo-controlled treatment (period 1) followed by a ...

  2. A Study to Compare Subcutaneous Daratumumab with Intravenous Daratumumab - Mayo Clinic

    The purpose of this study is to evaluate qualtiy of life (QOL) metrics while receiving subcutaneous (SQ) daratumumab, patient satisfaction, and patient ...

  3. A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study of ABT-494 for the Induction of Symptomatic and Endoscopic Remission in Subjects With Moderately to Severely Active Crohn's Disease Who Have Inadequately Responded to or Are Intolerant to Immunomodulators or Anti-TNF Therapy - Mayo Clinic

    A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study of ABT-494 for the Induction of Symptomatic and Endoscopic Remission in Subjects With ...

  4. A Study of an Easy-to-Read Informed Consent for Bone Marrow Transplant Clinical Trials

    Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and ...

  5. A Study to Evaluate Long-Term Outcomes of the Darrach in Patients 18-40 Years - Mayo Clinic

    About this study. The purpose of this study is to assess the long-term patient-reported, clinical, and radiographic outcomes of the Darrach procedure in ...

  6. A Registry to Track Scleroderma Progression - Mayo Clinic

    The purpose of this study is to to develop an early systemic sclerosis ((SSc), scleroderma defined as < 5 years from 1st non- Raynaud's Phenomenon (RP) symptom ...

  7. A Study to Develop a Large-Scale Long-Term Database of Headache Disorders - Mayo Clinic

    The purpose of this study is to enroll in a registry patients who have headache disorders, collecting detailed headache characteristics, biospecimens, and brain ...

  8. Safety and Efficacy of SA4Ag Vaccine in Adults Having Elective Open Posterior Spinal Fusion Procedures With Multilevel Instrumentation - Mayo Clinic

    About this study. The purposes of the clinical trial are to determine whether the SA4Ag vaccine can prevent postoperative Staphylococcus aureus infections ...

  9. Descriptive Analysis of Gut Microbiome Alterations in Hyperoxaluric Patients - Mayo Clinic

    About this study. To characterize the microbiome in 4 groups of subjects (primary hyperoxaluria type I (PH1), idiopathic CaOx stone, enteric hyperoxaluria ...

  10. Erlotinib with or without Bevacizumab in Treating Patients with Stage IV Non-Small Cell Lung Cancer with EGFR Mutations - Mayo Clinic

    Monoclonal antibodies, such as bevacizumab, can block tumor growth in different ways. Bevacizumab blocks the ability of tumors to grow new blood vessels and ...