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  1. Focus areas - Division of Clinical Trials and Biostatistics - Mayo Clinic Research

    Biomarker-stratified and biomarker enrichment designs. Cluster randomized trial designs. Collection and analysis of adverse event data in oncology trials.

  2. Safety and Efficacy of GS-5745 in Participants With Moderately to Severely Active Crohn's Disease - Mayo Clinic

    This study will primarily evaluate the safety and efficacy of GS-5745 in adults with active Crohn's disease. The study will consist of a Blinded Treatment ...

  3. A Study of Soundscapes for Patient Wellbeing - Mayo Clinic

    Also, to assess the impact of immersive soundscape on surgical staff stress and experience (ie. distraction) during an outpatient vascular surgery procedure.

  4. A Study of a New Recording Electrode to Record Brain Activity During Surgery - Mayo Clinic

    This research study will investigate a new recording electrode that will record brain activity during surgery. This electrode is being tested for efficacy, and ...

  5. Learning More about How your Brain Works with Decreased Levels of Oxygen - Mayo Clinic

    About this study. The specific aim of this proposal is (1) to develop a human model of hypoxia in which cerebrovascular reactivity and cognitive function ...

  6. A Study Associating Self Injuring Behavior and Flawed Sensory Mechanisms - Mayo Clinic

    About this study. The purpose of this study is to discover and to understand why some children with intellectual and developmental delays injure themselves.

  7. A Study to Predict Post-Surgery Symptom Outcomes with the Use of a Preoperative Pessary - Mayo Clinic

    The goal of the study is to evaluate the change in pelvic floor symptoms with pessary use prior to reconstructive pelvic floor surgery for pelvic organ prolapse ...

  8. Burnout Reduction and Engagement App-based Trial of Headspace (BREATHE): A Randomized Clinical Trial - Mayo Clinic

    The purpose of this study is to evaluate the impact of a mobile application-based intervention to reduce burnout and improve well-being among physicians and ...

  9. A Study of the Safety, Tolerability, and Drug/Body Interactions of C2N-8E12 in People with Progressive Supranuclear Palsy - Mayo Clinic

    The purpose of this study is to evaluate the safety, tolerability and drug/body interactions of C2N-8E12 in patients with progressive supranuclear palsy.

  10. Safety and Efficacy of Polymyxin B Hemoperfusion (PMX) for Endotoxemic Septic Shock in a Randomized, Open-Label Study - Mayo Clinic

    The purpose of this study is to compare the safety and effectiveness of the PMX cartridge (Toraymyxin) based on mortality at 28 days in patients with septic ...