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  1. Cabozantinib-S-Malate Compared With Temozolomide or Dacarbazine in Treating Patients With Melanoma of the Eye - Mayo Clinic

    Cabozantinib-s-malate may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, such as ...

  2. A Study to Evaluate Pevonedistat, Azacitidine (or Decitabine), and Venetoclax (PAVE) to Treat Acute Myelogenous Leukemia (AML) Patients - Mayo Clinic

    A Study to Evaluate Pevonedistat, Azacitidine (or Decitabine), and Venetoclax (PAVE) to Treat Acute Myelogenous Leukemia (AML) Patients · Share · Facebook ...

  3. A Study of the Safety and Effectiveness of HBI-8000 with Nivolumab to Treat Melanoma, Renal Cell Carcinoma and Non-Small Cell Lung Cancer - Mayo Clinic

    Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and ...

  4. A Study of the Combination of IMCgp100 with Durvalumab and/or Tremelimumab for Patients with Advanced Cutaneous Melanoma - Mayo Clinic

    The purpose of this study is to characterize the safety, tolerability, effectiveness, biological activity, and drug/body interactions of IMCgp100, alone and in ...

  5. Testing the Addition of Stereotactic Radiation Therapy With Immune Therapy for the Treatment of Patients With Unresectable or Metastatic Renal Cell Cancer, SAMURAI Study - Mayo Clinic

    The purpose of this study is to determine whether the addition of stereotactic ablative radiotherapy (SABR) to the primary tumor in combination with ...

  6. A Study to Determine the Safety, Tolerability and Effect on Liver Histologic Parameters of ARO-AAT - Mayo Clinic

    The purpose of this study is to evaluate the safety, tolerability and effect on liver histologic parameters with administration of the investigational product, ...

  7. A Study to Evaluate Pembrolizumab and Dasatinib, Imatinib Mesylate, or Nilotinib in Treating Patients with Chronic Myeloid Leukemia and Persistently- Detectable Minimal Residual Disease - Mayo Clinic

    Monoclonal antibodies, such as pembrolizumab, may interfere with the ability of cancer cells to grow and spread. Dasatinib, imatinib mesylate, and nilotinib may ...

  8. A Study of Atezolizumab as Adjuvant Therapy in Participants With Renal Cell Carcinoma (RCC) at High Risk of Developing Metastasis Following Nephrectomy - Mayo Clinic

    This is a Phase III, multicenter, randomized, placebo-controlled, double-blind study to evaluate the efficacy and safety of atezolizumab versus placebo in ...

  9. A Study of BBI608 in Combination With Standard Chemotherapies in Adult Patients With Advanced Gastrointestinal Cancer - Mayo Clinic

    This is an open label, multi-center, Phase Ib dose escalation study of BBI608 administered in combination with either FOLFOX6 with and without bevacizumab, or ...

  10. A Study to Determine the Effectiveness and Safety of Benralizumab for Patients with Severe Nasal Polyposis - Mayo Clinic

    The effect of benralizumab on nasal polyps will be assessed over a 56 weeks of treatment period in patients with severe bilateral nasal polyposis who are still ...