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  1. Review of the Safety and Effectiveness of the THERMOCOOL SMARTTOUCH® SF Catheter Evaluated for Treating Symptomatic PersistenT AF (PRECEPT) - Mayo Clinic

    This is a prospective, multicenter, non-randomized clinical evaluation utilizing the THERMOCOOL SMARTTOUCH® SF catheter compared to a predetermined performance ...

  2. To Compare the Efficacy and Safety of the HAV With AVF in Female Patients With End-Stage Renal Disease Requiring Hemodialysis (HUMAXX) - Mayo Clinic

    The purpose of this study is to compare the time (i.e., total days) free from indwelling hemodialysis (HD) catheter (“catheter-free days”), calculated from the ...

  3. A Study to Test Adding Pembrolizumab to Olaparib Alone as Therapy for Patients with Pancreatic Cancer That Has Spread with Inherited BRCA Mutations - Mayo Clinic

    The primary purpose of this study is to evaluate the progression free survival (PFS) of advanced pancreatic cancer patients with germline BRCA1 or BRCA2 ...

  4. Evaluation of the Zone-MPC Control Algorithm Integrated into the iAPS in Pregnant Patients with Type 1 Diabetes - Mayo Clinic

    The purpose of this research is to test the safety and effectiveness of the interoperable Artificial Pancreas System Smartphone App (iAPS) in managing blood ...

  5. A Study to Evaluate Patiromer for the Management of Hyperkalemia in Subjects Receiving Renin-Angiotensin Aldosterone System Inhibitor (RAASi) Medications for the Treatment of Heart Failure (DIAMOND) - Mayo Clinic

    About this study. The purpose of this study is to determine if patiromer treatment of subjects who developed hyperkalemia while receiving RAASi medications ...

  6. Dose Escalation and Expansion Study of GSK525762 in Combination With Fulvestrant in Subjects With Estrogen Receptor Positive (ER+) Breast Cancer - Mayo Clinic

    This is a combination Phase I and Phase II study, with an aim to evaluate the combination of GSK525762 and fulvestrant in women with advanced or metastatic ER+ ...

  7. Tradipitant After GLP-1R Agonist In Healthy, Overweight, or Class I or II Obese Volunteers - Mayo Clinic

    The purpose of this study is to evaluate the effect of tradipitant relative to placebo on proportion of subjects with at least 1 vomiting episode per week ...

  8. Clinical Trials - Continued Access to PREVAIL (CAP2)

    About this study. To provide additional information about the safety and efficacy of the WATCHMAN LAA Closure Technology.

  9. A Study to Evaluate the Effectiveness and Safety of Cobomarsen (MRG-106) vs. Active Comparator in Subjects with Mycosis Fungoides - Mayo Clinic

    Cobomarsen is designed to inhibit the activity of a molecule called miR-155 that may be important to the growth and survival of MF cancer cells. The study will ...

  10. MC200404, Safety and Immunogenicity of PolyPEPI1018 Vaccine in the Treatment of Late-stage Metastatic Colorectal Cancer - Mayo Clinic

    However, TAS-102 is FDA approved for treatment of metastatic colorectal cancer. The FDA has allowed the use of this combination in this research study.