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  1. Multicenter Automatic Defibrillator Implantation Trial With Subcutaneous Implantable Cardioverter Defibrillator - Mayo Clinic

    About this study. The MADIT S-ICD trial is designed to evaluate if subjects with a prior myocardial infarction, diabetes mellitus and a relatively preserved ...

  2. A Study to Screen Mothers for Metabolic Problems and Compare Treatment with Alternative Vitamin/Mineral Supplement - Mayo Clinic

    The purpose of this study is to screen mothers of young children with Autism Spectrum Disorders for metabolic problems, and find if it can be treated with a ...

  3. A Study to Evaluate the Mobility+ System and Its Usability - Mayo Clinic

    This evaluation will enable Rockfield Medical Devices to assess the usability of Mobility+, ensure user and patient safety are prioritized and adequate ...

  4. A Study of Using Caspofungin Acetate or Fluconazole in Preventing Invasive Fungal Infections in Patients with Acute Myeloid Leukemia Who Are Undergoing Chemotherapy - Mayo Clinic

    This randomized phase III trial studies caspofungin acetate to see how it works compared to fluconazole in preventing invasive fungal infections in patients ...

  5. A Study Comparing the Outcome of a Large-Diameter versus Small-Diameter Glenosphere (Shoulder/Arm Ball-Joint) in Primary Reverse Shoulder Arthroplasty - Mayo Clinic

    The purpose of this study is to compare the outcome of primary reverse shoulder arthroplasty using the Stryker ReUnion System with the implantation of either a ...

  6. Efficacy and Safety Study of Frexalimab (SAR441344) in Adults With Nonrelapsing Secondary Progressive Multiple Sclerosis - Mayo Clinic

    The purpose of this study is to determine the efficacy of frexalimab in delaying the disability progression and the safety up to approximately 51 months ...

  7. Validation of Gene Expression Markers of Renal Allograft Functional Decline - Mayo Clinic

    About this study. Researchers would like to see if it is possible to predict which transplanted kidneys will do better long term based on the gene ...

  8. A Study To Assess Efficacy And Safety Of Pembrolizumab With Or Without Sacituzumab Tirumotecan (MK- 2870) In Adult Participants With Resectable Non Small Cell Lung Cancer (NSCLC) Not Achieving Pathological Complete Response (pCR) (MK-2870-019) - Mayo Clinic

    This study will assess if adding sacituzumab tirumotecan with pembrolizumab after surgery is effective in treating NSCLC for participants not achieving ...

  9. Immunomodulation and Patients` Outcomes Following Treatment of Hepatocellular Carcinoma by Radiofrequency Ablation, Microwave Ablation, Trans-Arterial Chemoembolization or Radio-embolization - Mayo Clinic

    The goal of the study is to identify immune responses (immune cell activation and suppression) following local ablation of liver tumors. Participation ...

  10. Universal Rare Gene Study: A Registry and Natural History Study of Retinal Dystrophies Associated With Rare Disease-Causing Genetic Variants - Mayo Clinic

    The purpose of this registry is to establish genetically and clinically well-characterized cohorts of patients across hundreds of genetic variants associated ...