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  1. Efficacy and Safety of Tislelizumab in Combination With Fruquintinib in Participants With Selected Solid Tumors - Mayo Clinic

    The purpose of this research is to see how well fruquintinib works in combination with tislelizumab in participants with metastatic colorectal cancer (mCRC).

  2. Dose-Escalated Photon IMRT or Proton Beam Radiation Therapy Versus Standard-Dose Radiation Therapy and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma - Mayo Clinic

    Radiation therapy uses high-energy x-rays and other types of radiation to kill tumor cells and shrink tumors. Specialized radiation therapy that delivers a high ...

  3. Neoadjuvant dual checkpoint blockade with PD1 and LAG-3 inhibition in resectable Non-small cell lung Cancer - Mayo Clinic

    ... major pathologic response (MPR) (defined as ≤ 10% viable tumor cells in resected tumor and lymph nodes. To assess efficacy of neoadjuvant cemiplimab and ...

  4. PLX038 for the Treatment of Metastatic Ovarian, Peritoneal, and Fallopian Tube Cancers - Mayo Clinic

    The purpose of this study is to determine the response rate to PLX-038 in patients with metastatic ovarian, primary peritoneal, and fallopian tube cancers that ...

  5. Ponatinib Hydrochloride in Treating Patients With Advanced Biliary Cancer With FGFR2 Fusions - Mayo Clinic

    Ponatinib hydrochloride may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Participation eligibility. Participant ...

  6. A Study to Evaluate the Pharmacokinetics of Low-Dose Bevacuzimab in Reducing Free Plasma VEGF-A in Hemodialysis Patients - Mayo Clinic

    The purpose of this study is to see how hemodialysis patients respond to a very low dose of Avastin (bevacizumab) by measuring the concentration of the ...

  7. Alternate Doses and Dosing Schedules of Belantamab Mafodotin for the Treatment of Triple-Class Recurrent and/or Refractory Multiple Myeloma - Mayo Clinic

    The purpose of this study is to assess the 24-week grade 3/4 keratopathy-free rate of an alternative dose/dosing schedule for belantamab mafodotin in patients ...

  8. A Study of Sotatercept for the Treatment of Pulmonary Arterial Hypertension - Mayo Clinic

    The purpose of this study is to evaluate the effect of sotatercept (ACE-011) in adults with Pulmonary Arterial Hypertension. Each eligible participant will ...

  9. Carfilzomib and Melphalan Before Stem Cell Transplant in Treating Patients With Multiple Myeloma - Mayo Clinic

    Carfilzomib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, such as melphalan, work in ...

  10. A Study of the Safety and Effectiveness of the SAPIEN 3 Transcatheter Heart Valve in Low Risk Patients with Aortic Stenosis - Mayo Clinic

    The purpose of this study is to establish the safety and effectiveness of the Edwards SAPIEN 3 Transcatheter Heart Valve in patients who have severe, ...