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  1. Equipment and resources - Biomechanics Core - Mayo Clinic Research

    Kuka KR 300 R2500 Ultra F with muscle actuators and SimVitro universal musculoskeletal simulator control software. Zeiss ARAMIS SRX digital image correlation ...

  2. A Study to Validate DNA Methylation Markers for Universal and Site-specific Guided Cancer Detection - Mayo Clinic

    The purpose of this study is to validate candidate universal and site-specific methylated DNA markers (MDMs) in DNA extracted from formalin-fixed paraffin ...

  3. Targeting Pathways in Polycystic Ovary Syndrome (PCOS) Using Metformin (MET) - Mayo Clinic

    The investigators propose here to use both targeted and non-targeted metabolomic approach to identify pathways associated with metformin's effect on insulin ...

  4. Study of ASTX727 vs IV Decitabine in MDS and CMML - Mayo Clinic

    After completion of PK studies during the first 2 treatment cycles, subjects will continue to receive treatment with ASTX727 from Cycle 3 onward (in 28-day ...

  5. The Canadian CABG or PCI in Patients With Ischemic Cardiomyopathy Trial - Mayo Clinic

    Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and ...

  6. ACP-196 in Combination With Pembrolizumab, for Treatment of Hematologic Malignancies - Mayo Clinic

    The purpose of this study is to characterize the safety profile of acalabrutinib and pembrolizumab in subjects with hematologic malignancies. Participation ...

  7. Study to Evaluate Efficacy of LAI When Added to Multi-drug Regimen Compared to Multi-drug Regimen Alone - Mayo Clinic

    A study to evaluate the effectiveness of Liposomal Amikacin for Inhalation (LAI) when added to multi-drug regimen in subjects with Nontuberculous Mycobacterial ...

  8. A Long-term Active Treatment Study of Mongersen (GED-0301) in Subjects With Crohn's Disease - Mayo Clinic

    About this study. The purpose of this study is to assess long-term safety data of GED-0301 for a period of up to 208 weeks in adult subjects (i.e., ...

  9. A Study to Evaluate the Effectiveness and Safety of Ralinepag To Improve Treatment Outcomes in Peripheral Arterial Hypertension (PAH) Patients - Mayo Clinic

    About this study. To evaluate the efficacy and safety of ralinepag when added to pulmonary arterial hypertension (PAH) standard of care or PAH-specific ...

  10. Patient-Reported Outcome Questionnaire for Use Among Patients with Myelofibrosis After First Line Treatment Failure - Mayo Clinic

    About this study. The primary goal of this study is to inform and substantiate a measurement strategy and its regulatory documentation pursuant to United ...