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  1. Abnormal Glycosylation on the Hypothalamic-Pituitary Adrenal and -Gonadal Axes and Bone Health in Patients with Congenital Disorders of Glycosylation - Mayo Clinic

    About this study. The objectives of this study are to characterize the endocrine phenome of 60 patients with PMM2-CDG through a cross-sectional measurement ...

  2. Extended Regional Block following Arteriovenous Fistula Creation - Mayo Clinic

    The pump will be used to deliver 0.2% ropivacaine over the indicated 5-day period post-surgery. Five days was chosen based on the product's FDA approved ...

  3. A Study to Evaluate the Effectiveness of Antihistamines in the Treatment of Eosinophilic Esophagitis - Mayo Clinic

    Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and ...

  4. Improving Sympathetic Activity, Hot Flashes, and Sleep in Midlife Women Using Inspiratory Muscle Strength Training - Mayo Clinic

    The purpose of this research is to understand how training the muscles used for breathing (inhalation) affects menopausal hot flashes, sympathetic nerve ...

  5. A Study to Evaluate the Safety and Effectiveness of TT-00420 in Adults with Advanced Cholangiocarcinoma - Mayo Clinic

    Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and ...

  6. A Study of Subcutaneous Abatacept to Treat Diffuse Cutaneous Systemic Sclerosis - Mayo Clinic

    The purpose of this study is to assess the safety and effectiveness of subcutaneous abatacept in patients with diffuse cutaneous systemic sclerosis.

  7. A Study of CYP-001 in Combination With Corticosteroids in Adults With High-risk aGvHD - Mayo Clinic

    The purpose of this study is to evaluate the effectiveness of CYP-001 and CS vs placebo and CS in adults with HR-aGvHD based on Overall Response Rate (ORR) at ...

  8. A Multicentered Epilepsy Genetics Database - Mayo Clinic

    About this study. The purpose of this study is to develop a centralized national database of common and rare genetic etiologies of childhood-onset epilepsy ...

  9. Safety and Tolerability of Atezolizumab (ATZ) in Combination With Radium-223 Dichloride (R-223-D) in Metastatic Castrate-Resistant Prostate Cancer (CRPC) Progressed Following Treatment With an Androgen Pathway Inhibitor - Mayo Clinic

    This adaptive design study includes a cohort phase and a potential randomization phase. An initial concurrent dosing evaluation will evaluate the safety and ...

  10. Study of Pembrolizumab (MK-3475) in Combination With Dinaciclib (MK-7965) in Hematologic Malignancies (MK-3475-155) - Mayo Clinic

    During an initial Dose Evaluation phase (first 2 cycles) to determine Dose Limiting Toxicities (DLTs), dose combinations of pembrolizumab 200 mg followed by ...