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  1. Phase 2a Open-Label Pilot Study of VTX2735 in Recurrent Pericarditis - Mayo Clinic

    The purpose of this study is to evaluate the safety and tolerability of VTX2735 in participants with symptomatic recurrent pericarditis. Participation ...

  2. Testing the Addition of Cemiplimab to Palbociclib for the Treatment of Advanced Dedifferentiated Liposarcoma - Mayo Clinic

    The purpose of this study is to compare the effect of treatment with palbociclib alone to treatment with palbociclib plus cemiplimab for treating patients with ...

  3. A Study to Evaluate Intravenous Erenumab in Patients with Status Migrainosus - Mayo Clinic

    The purpose of this study is to investigate the use of erenumab 140mg IV in patients with status migrainosus. The specific aims of the study are to evaluate ...

  4. A Study to Assess the Efficacy and Safety of Risankizumab in Subjects With Moderately to Severely Active Crohn's Disease Who Failed Prior Biologic Treatment - Mayo Clinic

    The objective of Study M15-991 is to evaluate the efficacy and safety of risankizumab versus placebo during induction therapy in subjects with moderately to ...

  5. INCB161734 for Advanced or Metastatic Solid Tumors With KRAS G12D Mutation - Mayo Clinic

    The purpose of this study is to determine the safety and tolerability of INCB161734 as a single agent or in combination with other anticancer therapies.

  6. A Study to Evaluate the Effectiveness and Safety of Pembrolizumab Combined with Bacillus Calmette-Guerin in High-Risk Non-Muscle Invasive Bladder Cancer - Mayo Clinic

    The purpose of this study is to assess the antitumor efficacy and safety of pembrolizumab in combination with BCG, compared to BCG monotherapy, in participants ...

  7. A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Effect on Disease Progression of BIIB078 in Amyotrophic Lateral Sclerosis (ALS) Patients - Mayo Clinic

    The secondary objective is to evaluate the pharmacokinectics or movement of drug throughout the body (PK) of BIIB078 in participants with C9ORF72-ALS.

  8. A Study To Evaluate The Efficacy And Safety Of Sotagliflozin In Symptomatic Obstructive And Non-obstructive Hypertrophic Cardiomyopathy - Mayo Clinic

    The main purpose of the study is to determine the changes in symptoms and functional limitations in participants with symptomatic hypertrophic cardiomyopathy ( ...

  9. Study Evaluating the Antitumor Activity and Safety of Niraparib as Neoadjuvant Treatment - Mayo Clinic

    Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and ...

  10. Pazopanib Hydrochloride in Treating Patients with Advanced or Progressive Malignant Pheochromocytoma or Paraganglioma - Mayo Clinic

    Pazopanib hydrochloride may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth and by blocking blood flow to the tumor.