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1. A Study to Investigate the Safety and Effectiveness of SAPIEN 3 Transcatheter Heart Valve Implantation in Patients with a Failing Mitral Bioprosthetic Valve - Mayo Clinic

   The purpose of this study is to assess the safety and effectiveness of the SAPIEN 3 (Edwards Lifesciences, Irvine, California) transcatheter heart valve in ...

2. The Relationship Between Endoscopic Inflammation and Health-related Quality of Life in Patients with Ulcerative Colitis - Mayo Clinic

   About this study. Primary Aim. We aim to evaluate: 1) the correlation between patient-reported rectal bleeding and stool frequency and health-related ...

3. Microbiota Restoration Therapy for Recurrent Clostridium Difficile Infection (PUNCHCD3) - Mayo Clinic

   This is a prospective, multicenter, randomized, double-blinded, placebo-controlled Phase 3 study of a microbiota suspension of intestinal microbes. Patients who ...

4. Efficacy and Safety Trial of MK-8931 in Participants With Prodromal Alzheimer's Disease (MK-8931-019) - Mayo Clinic

   The purpose of this trial is to assess the efficacy and safety of MK-8931 compared with placebo in the treatment of amnestic mild cognitive impairment (aMCI) ...

5. A Single Patient Treatment Plan with Autologous Mesenchymal Stromal Cell Coated Fistula Plug in a Single Patient with Persistent Pouch-Vaginal Fistula - Mayo Clinic

   The purpose of this treatment plan is to use a treatment option only being used within a phase 1 research trial using an autologous mesenchymal stromal cell ( ...

6. A Study to Develop a Program for those Living Alone with Mild Cognitive Impairment - Mayo Clinic

   The purpose of this study is to develop a program for individuals living alone with mild cognitive impairment (MCI). Participation eligibility. Participant ...

7. Service Requests - Metabolomics Core - Mayo Clinic Research

   Metabolites are susceptible to a large number of "pre-analytic" sources of variability that should be addressed before samples are collected. The core staff has ...

8. Reverse Total Shoulder Arthroplasty Versus Open Reduction Internal Fixation in Patients Under 60 Years of Age - Mayo Clinic

   About this study. The purpose of this study is to evaluate the outcomes of RTSA versus ORIF in patients 60 years and younger who present with acute PHF, ...

9. Temperature Elevation During Total Knee Arthroplasty - Mayo Clinic

   About this study. The purpose of this research is to evaluate the temperature of the bone surface and saw blade that is reached during a total knee ...

10. Weight Loss in Parkinson's Disease and Role of Small Bowel Bacterial Overgrowth - Mayo Clinic

    About this study. The potential role of Small bowel bacterial overgrowth (SBBO) in weight loss occurring in patients with PD has not previously been ...