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  1. A Study to Evaluate MEDI2228 in Subjects with Relapsed/ Refractory Multiple Myeloma - Mayo Clinic

    About this study. The purpose of this study is to assess the safety, pharmacokinetics and tolerability, describe the dose-limiting toxicities (DLTs), ...

  2. A Randomized, Double-blind, Phase 3 Efficacy Trial of PROSTVAC-V/F +/- GM-CSF in Men With Asymptomatic or Minimally Symptomatic Metastatic Castrate-Resistant Prostate Cancer - Mayo Clinic

    The purpose of this study is to determine whether PROSTVAC alone or in combination with GM-CSF is effective in prolonging overall survival in men with few or no ...

  3. Study of TH-302 or Placebo in Combination With Pemetrexed in Patients With Non-squamous Non-small Cell Lung Cancer - Mayo Clinic

    Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and ...

  4. Study to Evaluate Eradicating Barrett's Esophagus Using Radiofrequency Ablation or a Novel Hybrid Argon Plasma Coagulation Technique - Mayo Clinic

    About this study. The purpose of this study is to investigate if Hybrid Argon Plasma Coagulation (HAPC) is non-inferior to Radiofrequency Ablation (RFA) in ...

  5. Biorepository of Biosamples From Patients With Psoriatic Arthritis in the Spondyloarthritis Research Program - Mayo Clinic

    Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and ...

  6. A Study of Low Intensity Mechanoreflex during Exercise in Healthy Adults - Mayo Clinic

    The purpose of this study is to investigate the effect of non-invasive low intensity venous distension on the activation of locomotor muscle group III afferents ...

  7. A Phase II Study Evaluating the Safety and Efficacy of Subcutaneous Plerixafor - Mayo Clinic

    About this study. This is a Phase II, open-label, two strata, multicenter, prospective study of plerixafor-mobilized HLA-identical sibling allografts in ...

  8. Polyphenon E in Treating Patients with High-Risk of Colorectal Cancer - Mayo Clinic

    Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and ...

  9. A Study to Assess the Safety and Antitumor Activity of Genetically Engineered T Cells in NY-ESO-1 and/or LAGE-1a Positive Solid Tumors - Mayo Clinic

    About this study. To evaluate the effectiveness of NY-ESO-1-Specific (c259) T Cells, alone or in combination with other anti-cancer agents, in HLA-A*02:01, ...

  10. A Study Evaluate the Positive Impact of Canine Therapy on Cardiac Rehab Patient Outcomes - Mayo Clinic

    The purpose of this study is to compare resting blood pressure, heart rate, and quality of life outcomes in cardiac rehab patients with canine involvement ...