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  1. A Study to Find the Recommended Dose for Further Research for VX-970 and Whole Brain Radiation Therapy to Treat Patients with Brain Metastases from Non-Small Cell Lung Cancer - Mayo Clinic

    The purpose of this study is to assess the side effects and best dose of ATR kinase inhibitor VX-970 when given together with whole brain radiation therapy for ...

  2. Defibrotide for Patients with Hepatic Veno-occlusive Disease: A Treatment IND Study - Mayo Clinic

    Single arm, open-label study to provide Defibrotide to patients diagnosed with VOD. Defibrotide is no longer available though the Emergency Use IND mechanism ( ...

  3. Anterior Vaginal Prolapse Clinical Trials - Mayo Clinic Research

    The goal of the study is to evaluate the change in pelvic floor symptoms with pessary use prior to reconstructive pelvic floor surgery for pelvic organ prolapse ...

  4. Core Services and Tools - Genetics Epigenetics and Metabolomics Core - Mayo Clinic Research

    The Genetics, Epigenetics and Metabolomics Core at Mayo Clinic offers six main PKD services for research and tools for polycystic kidney disease.

  5. Student Profiles - Center for Clinical and Translational Science

    Student Profiles. Laboratory-based basic research. Students conducting research on the underlying pathophysiology of diseases; markers of disease presence, ...

  6. A Phase 2 Study to Evaluate Pharmacodynamics of YKP10811 in Patients With Chronic or Functional Constipation - Mayo Clinic

    About this study. This will be a single-center, randomized, parallel group, multiple dose administration, double-blind, placebo-controlled study to evaluate ...

  7. A Study of Tucatinib With Trastuzumab and mFOLFOX6 Versus Standard of Care Treatment in First-line HER2+ Metastatic Colorectal Cancer (MOUNTAINEER-03) - Mayo Clinic

    The purpose of this study is to find out if tucatinib with other cancer drugs works better than standard of care to treat participants with HER2 positive ...

  8. Long Term Follow Up Study of the St. Jude Medical Trifecta Valve - Mayo Clinic

    Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and ...

  9. Phase 1/2, Open Label, Dose Escalation Study of NEOD001 in Subjects With Light Chain (AL) Amyloidosis - Mayo Clinic

    Dose escalation study to determine the maximum tolerated dose of NEOD001 in approximately 30 subjects with AL amyloidosis. Expansion phase to evaluate safety, ...

  10. Young-adult normal FDG-PET database - Mayo Clinic

    About this study. The purpose of this study is to construct a young-adult normative FDG database that could be used with Cortex-ID and/or MIMneuro, ...