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1. A Study to Optimize Patient Selection and Outcomes in Laryngeal Vascular Composite Allograft Transplantation - Mayo Clinic

   In-depth qualitative interviews will be performed to explore beliefs of laryngotracheal transplant candidates, their caregivers, and clinicians about their ...

2. Outcomes of Positive Pressure Therapy for Obstructive Sleep Apnea Following Endoscopic Sinus Surgery - Mayo Clinic

   The purpose of this study is to: Evaluate if there are detrimental effects of restarting CPAP therapy on POD #0-1 in patients undergoing ESS compared to normal ...

3. Biospecimens analysis in healthy controls - Mayo Clinic

   The purpose of this study is to collect healthy patient samples and give us a normal patient levels of antibodies, cytokines and other meaningful biomarkers ...

4. Study Comparing Veliparib Plus FOLFIRI Versus Placebo Plus FOLFIRI With or Without Bevacizumab in Previously Untreated Metastatic Colorectal Cancer - Mayo Clinic

   FOLFIRI is a chemotherapy regimen of fluorouracil, leucovorin and irinotecan. This is a blinded study such that the Investigator and Subject will be blinded but ...

5. A Study to Assess Whether Macitentan Delays Disease Progression in Children With Pulmonary Arterial Hypertension (PAH) - Mayo Clinic

   This is a prospective, multicenter, open-label, randomized, controlled, parallel group, group-sequential, event-driven Phase 3 study to evaluate efficacy, ...

6. Brightline-1: A Study to Compare Bi 907828 With Doxorubicin In People With a Type of Cancer Called Dedifferentiated Liposarcoma - Mayo Clinic

   Doxorubicin is a medicine already used to treat cancer including liposarcoma. During the study, participants get either BI 907828 or doxorubicin. Every 3 weeks, ...

7. Lactic Acid Samples During Cardiopulmonary Exercise Testing - Mayo Clinic

   The purpose of this study is to determine if point of care capillary lactic acid samples obtained from the fingertip during a stress echocardiography exam will ...

8. Clinical Trial of Upfront Haploidentical or Unrelated Donor Bmt to Restore Normal Hematopoiesis in Aplastic Anemia

   The purpose of this study is to increase options for severe aplastic anemia, allowing HSCT to be considered as a potential treatment by using a novel GVHD ...

9. A Study to Evaluate Increasing Lung Transplant Availability Using Normothermic Ex Vivo Lung Perfusion (EVLP) at a Dedicated EVLP Facility - Mayo Clinic

   The purpose of this study is to evaluate the safety and effectiveness of the Centralized Lung Evaluation System (CLES) in enabling evaluation of potential donor ...

10. A Study to Compare Tisagenlecleucel vs. Standard of Care in Adult Patients with Aggressive B-cell Non-Hodgkin Lymphoma - Mayo Clinic

    This is a randomized, open label, multicenter phase III trial to determine the efficacy and safety of tisagenlecleucel treatment strategy in adult patients with ...