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1. A Study to Evaluate Placental Pathologies Using Ultrasound of the Human Placenta - Mayo Clinic

   The purpose of this study is to develop an ultrasound method to identify villitis of unknown etiology (VUE)-induced inflammation in the human placenta during ...

2. Efficacy and Safety Study of Mepolizumab in Subjects With Severe Hypereosinophilic Syndrome (HES) - Mayo Clinic

   About this study. Mepolizumab is a humanized monoclonal antibody. In conditions where eosinophilia is considered to play an important part in the pathology, ...

3. A Study of the Safety, Effectiveness and Maximum Tolerated Dose of Oral PQR309 for Patients with Advanced Solid Tumors - Mayo Clinic

   The purpose of this study is to evaluate the safety, effectiveness and the maximum tolerable dose of PQR309 for the treatment of selected patients who have ...

4. An Open-label Study to Assess the Anti-Tumor Activity and Safety of REGN1979, an Anti-CD20 X Anti-CD3 Bispecific Antibody, in Patients with Relapsed or Refractory B-cell Non-Hodgkin Lymphoma - Mayo Clinic

   An Open-label Study to Assess the Anti-Tumor Activity and Safety of REGN1979, an Anti-CD20 X Anti-CD3 Bispecific Antibody, in Patients with Relapsed or ...

5. A Study of Using Botox to Decrease the Rate of Ventral Hernias Caused by Damage Control Laparotomy - Mayo Clinic

   The purpose of this study is to compare the rate of developing a ventral hernia after a damage control laparotomy between patients who had Botox induced ...

6. Improving Sympathetic Activity, Hot Flashes, and Sleep in Midlife Women Using Inspiratory Muscle Strength Training - Mayo Clinic

   The purpose of this research is to understand how training the muscles used for breathing (inhalation) affects menopausal hot flashes, sympathetic nerve ...

7. A Study to Evaluate Skin Angiosarcoma Imaging with Ultrasound - Mayo Clinic

   The patient will be scanned with a commercially avilable GE Logiq 10 machine and then with the 25-30 MHz linear microvessel transducer for microvessel imaging.

8. A Study to Assess Kidney Function Markers in Transgender Individuals Receiving Gender-affirming Hormone Therapy - Mayo Clinic

   The purpose of this study is to determine how cystatin C, creatinine, and microalbuminuira change with gender affirming hormone therapy initiation. Blood draws ...

9. Preclinical investigation of immunotherapeutic efficacy and safety of a novel oncolytic vesicular stomatitis virus expressing extracellular matrix-destructing enzymes in combination with immune checkpoint inhibitors in pancreatic adenocarcinoma - Mayo Clinic

   About this study. The purpose of this study is to bioengineer a novel vesicular stomatitis virus (VSV) to express extracellular matrix (ECM) destructing ...

10. A Study to Evaluate Molecular and Biochemical Testing for Suspected Hereditary Disorders - Mayo Clinic

    About this study. The objectives of this study are to perform molecular and/or biochemical testing in individuals with suspected hereditary disorders, ...