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  1. A Study to Evaluate Trifluridine/Tipiracil in Combination with Irinotecan to Treat Biliary Tract Cancers - Mayo Clinic

    The purpose of this study is assess the effectiveness of trifluridine/tipiracil plus irinotecan in treating advanced, refractory biliary tract cancers (BTCs).

  2. Diaphragm Ultrasound in Normal and Diseased Subjects - Mayo Clinic

    About this study. The purpose of this study is to compare diaphragm excursion (measured with B mode ultrasound) in a small group of healthy subjects with ...

  3. Blinatumomab and Combination Chemotherapy or Dasatinib, Prednisone, and Blinatumomab in Treating Older Patients With Acute Lymphoblastic Leukemia - Mayo Clinic

    The purpose of this study is to test any good and bad effects of adding the drug Blinatumomab to different doses of standard combination of chemotherapy drugs.

  4. A Study to Optimize Patient Selection and Outcomes in Laryngeal Vascular Composite Allograft Transplantation - Mayo Clinic

    In-depth qualitative interviews will be performed to explore beliefs of laryngotracheal transplant candidates, their caregivers, and clinicians about their ...

  5. Vorinostat, Temozolomide, or Bevacizumab in Combination with Radiation Therapy Followed by Bevacizumab and Temozolomide in Young Patients with Newly Diagnosed High-Grade Glioma - Mayo Clinic

    Vorinostat may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, such as temozolomide, work in ...

  6. Safety and Efficacy Study of PRI-724 in Subjects With Advanced Solid Tumors - Mayo Clinic

    PRI-724 is a new investigational drug being studied to treat subjects with cancer who have advanced solid tumors. PRI-724 is thought to work by blocking the Wnt ...

  7. Coronary Sinus Reducer For The Management Of Symptomatic Heart Failure - Mayo Clinic

    The purpose of this study is to evaluate the efficacy of CS Reducer implantation in patients with HFpEF and CMD on left ventricular filling pressures, ...

  8. Study to Assess the Safety, Tolerability, Efficacy and PK of APL-2 in Patients With wAIHA or CAD - Mayo Clinic

    This study is to assess the safety, tolerability, preliminary efficacy, and pharmacokinetics of APL-2 in subjects with warm Autoimmune Hemolytic Anemia (wAIHA) ...

  9. Bone cancer - Doctors and departments - Mayo Clinic

    Bone cancer most commonly affects the long bones in the arms and legs. Some types happen mostly in children, while others affect mostly adults.

  10. Perceived Financial Hardship in Patients with Multiple Myeloma and Their Caregivers - Mayo Clinic

    About this study. The purpose of the study is to examine the agrrement in perception of finacial hardship (FH) and the perceived stress in patients with ...