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  1. A Study to Assess the Safety and Tolerability of CFT8634 in Locally Advanced or Metastatic SMARCB1-Perturbed Cancers, Including Synovial Sarcoma and SMARCB1-Null Tumors - Mayo Clinic

    Phase 2 only: To assess preliminary antitumor activity by overall response rate (ORR) as measured by Response Evaluation Criteria in Solid Tumors (RECIST) v1.1 ...

  2. A Study of Macitentan in Pulmonary Hypertension After Left Ventricular Assist Device Implantation - Mayo Clinic

    About this study. The purpose of this study is to evaluate the effect of macitentan 10 mg on pulmonary vascular resistance as compared to placebo in ...

  3. A Study of Carboplatin, Cabazitaxel and Abiraterone in High Volume Metastatic Castration Sensitive Prostate Cancer (CASCARA) - Mayo Clinic

    The primary objective of this study is to determine the proportion of patients who have no PSA or radiographic progression as determined by RECIST 1.1 or PCWG3 ...

  4. A Study to Evaluate Blood Chemistry, Genetics, and Eye Exams in Women with Polycystic Ovary Syndrome and/or Idiopathic Intracranial Hypertension - Mayo Clinic

    Similar studies are being completed with astronauts. The results may help us better understand the nature, and ultimately the treatment of polycystic ovary ...

  5. Proton Pump Inhibitor (PPI) Responsive Eosinophilic Esophagitis EoE: Gastroesophageal Reflux Disease (GERD) or Eosinophilic Esophagitis (EoE)? - Mayo Clinic

    About this study. The investigators would like to determine if there are patients with PPI responsive Eosinophilic Esophagitis Infiltration that have ...

  6. A Study to Assess Characteristics of the Aorta Artery Using Heart Echo - Mayo Clinic

    The purpose of this study is to measure the characteristics of the walls of an enlarged aortic blood vessel using non-invasive heart echo to help predict how ...

  7. Optimizing Sleep/Wake Related Cognitive Efficacy - Mayo Clinic

    About this study. This is a pilot study designed to elucidate sleep/wake patterns and associated cognitive efficacy of laborists involved in shift work at ...

  8. A Study of Rucaparib in Patients With Platinum-Sensitive, Relapsed, High-Grade Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cancer (ARIEL2) - Mayo Clinic

    The purpose of this study is to determine which patients with ovarian, fallopian tube, and primary peritoneal cancer will best respond to treatment with ...

  9. Hospital Admission in Heart Failure: Readiness for Discharge and Predicting Future Admissions - Mayo Clinic

    Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and ...

  10. A Study of I-DXd in Combination With Atezolizumab With or Without Carboplatin as First-Line Induction or Maintenance in Subjects With Extensive Stage-Small Cell Lung Cancer (IDeate-Lung03) - Mayo Clinic

    About this study. The purpose of this study is to evaluate the safety and efficacy of I-DXd in combination with immune checkpoint inhibitor atezolizumab ...