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  1. A Study of Inorganic Nitrite Delivery to Improve Exercise Capacity in Patients with Heart Failure with a Preserved Ejection Fraction - Mayo Clinic

    The purpose of this study is to assess the effect of inorganic nitrite on aerobic capacity (peak VO2) after four weeks of giving it to patients who have heart ...

  2. Study of Natriuretic Peptide Receptor 1 (NPR1) Antagonist in Adult Patients With Postural Orthostatic Tachycardia Syndrome (POTS) - Mayo Clinic

    About this study. This study is researching an experimental drug called REGN7544 (called "study drug"). The study is focused on participants with POTS.

  3. A Study to Evaluate LB1148 for Return of Gastrointestinal Function and Adhesions in Subjects Undergoing Bowel Resection - Mayo Clinic

    Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and ...

  4. Consent for Prenatal Screening in Diverse Populations (Aim 1) - Mayo Clinic

    Prenatal providers will identify key clinical components of JITC and potential barriers to informed decision-making for PGS that JITC may have the potential to ...

  5. Endpoint Determination Study Protocol - Clinical Trials

    The purpose of this study is to evaluate the most applicable endpoints for evaluation of the Biomerica InFoods® IBS product. Participation eligibility.

  6. Study to Evaluate Efficacy and Safety of Two Drug Regimens in Subjects with Moderate to Severe Crohn's Disease - Mayo Clinic

    This study will evaluate the efficacy and safety of two adalimumab induction regimens in subjects with moderately to severely active Crohn's disease and ...

  7. Randomized, Open Label, Clinical Study of the Targeted Therapy, Palbociclib, to Treat Metastatic Breast Cancer

    About this study. The primary objective of this study is to demonstrate that the combination of palbociclib with anti-HER2 therapy plus endocrine therapy is ...

  8. Study to Evaluate the Efficacy and Safety of MEDI9929 (AMG 157) in Adult Subjects With Inadequately Controlled, Severe Asthma - Mayo Clinic

    The primary objective of the study is to evaluate the effect of 3 dose levels of MEDI9929 (AMG 157) on asthma exacerbations in adult subjects with inadequately ...

  9. Reverse Total Shoulder Arthroplasty versus Nonoperative Treatment of 3 & 4-Part Proximal Humerus Fractures - Mayo Clinic

    This purpose of this study is to answer if patients fair better with non-operative management or reverse total arthroplasty for treatment of 3- and 4-part ...

  10. Characterization of Biliary Cell-derived Organoids from Bile of PSC and Non-PSC Patients - Mayo Clinic

    About this study. The objectives of this study are to establish and perpetuate human biliary cell-derived organoids, to assess genetic and signaling pathway ...