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  1. A Study to Assess Safety and Effectiveness of Venetoclax in Combination With Gilteritinib in Subjects With Relapsed/Refractory Acute Myeloid Leukemia - Mayo Clinic

    About this study. The purpose of this dose-escalation study is to evaluate the safety, tolerability, pharmacokinetics (PK) and effectiveness of venetoclax, ...

  2. A Open Label Study of the Efficacy and Safety of PD0332991 a Selective Inhibitor of the Cyclin Dependent Kinases 4 and 6 in Patients With Recurrent Ovarian Cancer Demonstrating Rb-proficiency and Low p16 Expression - Mayo Clinic

    The purpose of this study is to obtain an estimate of the biochemical response rate as determined by CA125 response using the Gynecologic Cancer Intergroup ( ...

  3. Hodgkin lymphoma (Hodgkin disease) - Doctors and departments - Mayo Clinic

    Learn how this cancer differs from other lymphomas. Find out about risk factors and treatments, such as chemotherapy, radiation and bone marrow transplant.

  4. Selinexor in Advanced Liposarcoma - Clinical Trials

    This is a randomized, multicenter, double-blind, placebo-controlled, Phase 2-3 study of patients diagnosed with advanced unresectable dedifferentiated ...

  5. Study of INCB053914 in Subjects With Advanced Malignancies - Mayo Clinic

    About this study. This is an open-label, dose-escalation study of the proviral integration site of Moloney murine leukemia virus (PIM) kinase inhibitor ...

  6. A Study of NGM282 When Given to Subjects with Functional Constipation and to Healthy Individuals - Mayo Clinic

    The purpose of this study is to determine the effect of NGM282 on colonic transit, bile acid homeostasis, and fecal fat in subjects with functional constipation ...

  7. A Study to Evaluate Fogging in Scleral Contact Lens - Mayo Clinic

    About this study. The purpose of this study is to quantify potential decreases in visual acuity experienced by patients who experience mid-day fogging ...

  8. A Study to Evaluate the Effectiveness, Safety, Pharmacokinetics and Pharmacodynamics of Idasanutlin Monotherapy in Participants With Hydroxyurea-Resistant/Intolerant Polycythemia Vera - Mayo Clinic

    The purpose of this study is to evaluate the safety and effectiveness of idasanutlin monotherapy in participants with hydroxyurea (HU)-resistant/intolerant ...

  9. Contact - Imaging Core - Mayo Clinic Research

    Contact the Imaging and Analysis Core of the Mayo Clinic Pirnie Translational Polycystic Kidney Disease Center about protocol development, study design, ...

  10. A Study to Validate DNA Methylation Markers for Universal and Site-specific Guided Cancer Detection - Mayo Clinic

    The purpose of this study is to validate candidate universal and site-specific methylated DNA markers (MDMs) in DNA extracted from formalin-fixed paraffin ...