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  1. Study to Evaluate the Safety and Effectiveness of BMS-986036 in Adults with Nonalcoholic Steatophepatitis (NASH) and Compensated Liver Cirrhosis - Mayo Clinic

    The purpose of this study is to evaluate the safety and effectiveness of BMS-986036 in adults with nonalcoholic steatophepatitis (NASH) and compensated liver ...

  2. A Multi-Center Study Evaluating KTE-X19 in Pediatric and Adolescent Subjects With Relapsed/Refractory B-precursor Acute Lymphoblastic Leukemia - Mayo Clinic

    This is a single arm, open-label, multi-center, phase 1/2 study, to determine the safety and efficacy of KTE-X19, an autologous anti-CD19 chimeric antigen ...

  3. Study of EXE-346 Live Biotherapeutic to Reduce High Bowel Movement Frequency in Subjects With an IPAA (PROF) - Mayo Clinic

    The aim of this study is to assess the safety and preliminary efficacy of treatment with EXE-346, a live biotherapeutic, which may reduce bowel movement ...

  4. A Study of BBI608 in Combination With Standard Chemotherapies in Adult Patients With Advanced Gastrointestinal Cancer - Mayo Clinic

    This is an open label, multi-center, Phase Ib dose escalation study of BBI608 administered in combination with either FOLFOX6 with and without bevacizumab, or ...

  5. A Phase 3 Randomized, Placebo-controlled, Double-blind Study of Niraparib in Combination with Abiraterone Acetate and Prednisone Versus Abiraterone Acetate and Prednisone for Treatment of Subjects with Metastatic Prostate Cancer - Mayo Clinic

    A Phase 3 Randomized, Placebo-controlled, Double-blind Study of Niraparib in Combination with Abiraterone Acetate and Prednisone Versus Abiraterone Acetate ...

  6. Treatment of Thrombocytopenia in Patients With Chronic Liver Disease Undergoing an Elective Procedure - Mayo Clinic

    The study will evaluate avatrombopag in the treatment of thrombocytopenia associated with liver disease prior to an elective procedure to reduce the need for ...

  7. A Study to Investigate the Effectiveness of AMT-101 in Subjects with Chronic Antibiotic-resistant Pouchitis - Mayo Clinic

    The purpose of this study is to assess the safety, tolerability, and effectiveness of AMT-101 in subjects with chronic antibiotic-resistant pouchitis, and to ...

  8. A Study to Evaluate the Effectiveness and Safety of PANZYGA in Pediatric Patients with Chronic Immune Thrombocytopenia (ITP) - Mayo Clinic

    The purpose of this study is to evaluate the effectiveness and safety of PANZYGA in pediatric patients with chronic Immune Thrombocytopenia (ITP). Participation ...

  9. Phase 2a Open-Label Pilot Study of VTX2735 in Recurrent Pericarditis - Mayo Clinic

    The purpose of this study is to evaluate the safety and tolerability of VTX2735 in participants with symptomatic recurrent pericarditis. Participation ...

  10. Study of Encorafenib + Cetuximab Plus or Minus Binimetinib vs. Irinotecan/Cetuximab or Infusional 5-Fluorouracil (5-FU)/Folinic Acid (FA)/Irinotecan (FOLFIRI)/Cetuximab With a Safety Lead-in of Encorafenib + Binimetinib + Cetuximab in Patients With BRAF V600E-mutant Metastatic Colorectal Cancer - Mayo Clinic

    Study of Encorafenib + Cetuximab Plus or Minus Binimetinib vs. Irinotecan/Cetuximab or Infusional 5-Fluorouracil (5-FU)/Folinic Acid (FA)/Irinotecan ...