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  1. A Study to Evaluate Safety and Tolerability of Aducanumab in Participants With Alzheimer's Disease Who Had Previously Participated in the Aducanumab Studies - Mayo Clinic

    Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and ...

  2. Sapanisertib or Pazopanib Hydrochloride in Treating Patients With Locally Advanced or Metastatic Sarcoma - Mayo Clinic

    About this study. This partially randomized phase I/II trial studies the side effects and best dose of sapanisertib and to see how well it works compared to ...

  3. Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial - Mayo Clinic

    About this study. Carotid revascularization for primary prevention of stroke (CREST-2) is two independent multicenter, randomized controlled trials of ...

  4. A Study to Evaluate Intravenous Erenumab in Patients with Status Migrainosus - Mayo Clinic

    The purpose of this study is to investigate the use of erenumab 140mg IV in patients with status migrainosus. The specific aims of the study are to evaluate ...

  5. A Study to Evaluate the Safety, Effectiveness and Tolerability of APG-2575 in Patients with Waldenström Macroglobulinemia - Mayo Clinic

    About this study. The purpose of this study is to assess the safety and tolerability, identify dose-limiting toxicities (DLT) and the maximum tolerated dose ...

  6. Ixazomib Plus Pomalidomide and Dexamethasone in Treating Patients with Relapsed or Relapsed/Refractory Multiple Myeloma - Mayo Clinic

    Giving ixazomib with pomalidomide and dexamethasone may be an effective treatment for relapsed or relapsed/refractory multiple myeloma. Participation ...

  7. A world-class healthcare option - Mayo Clinic

    A team of nine specialists performed ground-breaking surgery which saved Janis Ollson's life. Read Janis' story.

  8. Testing Cabozantinib in Patients With Advanced Pancreatic Neuroendocrine and Carcinoid Tumors - Mayo Clinic

    Cabozantinib S-malate is a chemotherapy drug known as a tyrosine kinase inhibitor, and it targets specific tyrosine kinase receptors, that when blocked, may ...

  9. A Study to Evaluate the Effectiveness and Safety of G10 in Subjects with Transthyretin Amyloid Cardiomyopathy - Mayo Clinic

    The purpose of this study is to evaluate AG10 800 mg compared to placebo in subjects with symptomatic Transthyretin Amyloid Cardiomyopathy (ATTR-CM).

  10. Oxaliplatin, Leucovorin Calcium, and Fluorouracil With or Without Bevacizumab in Treating Patients Who Have Undergone Surgery for Stage II Colon Cancer - Mayo Clinic

    About this study. This randomized phase III trial studies oxaliplatin, leucovorin calcium, fluorouracil, and bevacizumab to see how well they work compared ...