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  1. Brain Cancer - Discovery and Translation Labs - Mayo Clinic Research

    Researchers in this cancer focus area of the Discovery and Translation Labs at Mayo Clinic study brain cancer, including metastatic tumors, stem cells and ...

  2. A Study to Assess the Effectiveness and Safety of Ublituximab in combination with Umbralisib and Venetoclax (U2-V) Compared to Ublituximab and Umbralisib (U2) in Subjects with Chronic Lymphocytic Leukemia (CLL) - Mayo Clinic

    Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and ...

  3. Collection of Tissue and Blood in Patients with Allergic and Immunologic Disorders - Mayo Clinic

    About this study. Allergic and immunologic disorders are very common but some are very poorly understood. Numerous studies of the epidemiology, ...

  4. A Study to Determine Baseline Levels for Prostate Cancer-Derived Particles Containing Cellular Matter (Extracellular Vesicles) After Local Treatment - Mayo Clinic

    About this study. The purposes of this study are to determine the levels of prostate cancer-derived extracellular vesicles pre- and post-local therapy ...

  5. A Randomized, Double-blind, Phase 3 Efficacy Trial of PROSTVAC-V/F +/- GM-CSF in Men With Asymptomatic or Minimally Symptomatic Metastatic Castrate-Resistant Prostate Cancer - Mayo Clinic

    The purpose of this study is to determine whether PROSTVAC alone or in combination with GM-CSF is effective in prolonging overall survival in men with few or no ...

  6. Blinatumomab and Combination Chemotherapy or Dasatinib, Prednisone, and Blinatumomab in Treating Older Patients With Acute Lymphoblastic Leukemia - Mayo Clinic

    The purpose of this study is to test any good and bad effects of adding the drug Blinatumomab to different doses of standard combination of chemotherapy drugs.

  7. A Study to Evaluate Cardiovascular Effects of High Intensity Interval Training in Individuals with Paraplegia - Mayo Clinic

    The purpose of this study is to produce preliminary data testing the feasibility and effectiveness of high intensity interval training (HIIT) on cardiovascular ...

  8. Clinical Study to Evaluate Mavacamten (MYK-461) in Adults With Symptomatic Obstructive Hypertrophic Cardiomyopathy

    This is a multicenter, international, double-blind study of the administration of mavacamten in participants with symptomatic obstructive HCM (oHCM).

  9. Phase 1-2 Study of ADXS11-001 or MEDI4736 Alone or Combo In Cervical or HPV+ Head & Neck Cancer - Mayo Clinic

    About this study. Part A: (ADXS11-001 + MEDI4736 Combination Therapy) will determine the safety and tolerability of the combination and to identify a RP2D.

  10. A Study Using Avelumab in Non-Small Cell Lung Cancer that has Progressed - Mayo Clinic

    The purpose of this study is to demonstrate avelumab's overall survival superiority versus docetaxel in patients with programmed death ligand 1 (PD-L1) positive ...