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  1. A Study of the Safety and Effectiveness of Combined Toca 511 and Toca FC for Patients Having Removal Surgery for Recurring Glioblastoma or Anaaplastic Astrocytoma - Mayo Clinic

    Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and ...

  2. A Quality of Life Assessment of Patients with Biliary Obstruction Undergoing Endoscopic or Percutaneous Drainage - Mayo Clinic

    The quality of life of patients witll be assessed using the validated "European Quality of Life-5 Dimensions Questionnaire" and the "Intervention-Dependent ...

  3. A Study Evaluating the Long-Term Effectiveness and Safety of Ralinepag in Subjects with PAH Via an Open-Label Extension - Mayo Clinic

    The purpose of this study is to evaluate the long-term safety and tolerability of ralinepag (APD811) in subjects who have participated in a preceding Phase 2 or ...

  4. Study to Assess the Safety, Tolerability, and Pharmacodynamic (PD) Effects of FRM-0334 in Subjects With Prodromal to Moderate Frontotemporal Dementia With Granulin Mutation - Mayo Clinic

    Study to Assess the Safety, Tolerability, and Pharmacodynamic (PD) Effects of FRM-0334 in Subjects With Prodromal to Moderate Frontotemporal Dementia With ...

  5. Phase 1 Crohn's Pediatric Sub-study of MSC AFP - Mayo Clinic

    The investigators propose to study the safety of autologous mesenchymal stromal cell transfer using a biomatrix (the Gore Bio-A Fistula Plug) in a Phase I study ...

  6. Pazopanib Hydrochloride and Topotecan Hydrochloride in Treating Patients With Metastatic Soft Tissue and Bone Sarcomas - Mayo Clinic

    About this study. The purpose of this clinical research study is to learn if pazopanib when given in combination with topotecan can help to control sarcomas ...

  7. Implementation of Meaning-Centered Psychotherapy for Veterans with Advanced Cancer - Mayo Clinic

    The purpose of this study is to evaluate the effectiveness of MCP on depression, psychosocial distress, and QOL in veterans with advanced cancer. This study ...

  8. PRE-I-SPY Phase I/Ib Oncology Platform Program - Mayo Clinic

    The purpose of the study is to evaluate single agents or combinations in a metastatic treatment setting that may be relevant for breast cancer patients with the ...

  9. A Phase II, Randomized, Double-blind, Placebo-controlled Study to Examine the Effects of DAS181 in Immunocompromised Subjects With Lower Respiratory Tract Parainfluenza Infection on Supplemental Oxygen - Mayo Clinic

    A Phase II, Randomized, Double-blind, Placebo-controlled Study to Examine the Effects of DAS181 in Immunocompromised Subjects With Lower Respiratory Tract ...

  10. CD-NP (Cenderitide) Therapy for the Preservation of Left Ventricular Function Post Anterior Myocardial Infarction - Pilot Study - Mayo Clinic

    About this study. The primary endpoint is to assess the safety and tolerability of CD-NP with the incidence of symptomatic hypotension being one of the key ...