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1. A Study to Evaluate Lumasiran in Children and Adults With Primary Hyperoxaluria Type 1 - Mayo Clinic

   Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and ...

2. ENVISION IDE Trial: Safety and Effectiveness of NAVITOR in Transcatheter Aortic Valve Implantation - Mayo Clinic

   About this study. The objective of ENVISION is to evaluate the safety and effectiveness of the Navitor Transcatheter Aortic Valve Implantation (TAVI) System ...

3. A Study Evaluating Respiratory Causes Impacting Pilot Performance - Mayo Clinic

   Task 1, entitled "Variable Oxygen Concentration Study," is to evaluate the three exposure variables through three study aims - differing on the oscillation ...

4. Daunorubicin Hydrochloride, Cytarabine, and Nilotinib in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia - Mayo Clinic

   This phase II trial studies how well daunorubicin hydrochloride, cytarabine, and nilotinib work in treating patients newly diagnosed with acute myeloid leukemia ...

5. A Study to Compare the Effectiveness of Invasive versus Conservative Medical Approaches in Patients with Stable Ischemic Heart Disease and Advanced Chronic Kidney Disease - Mayo Clinic

   About this study. The purpose of the ISCHEMIA-CKD trial is to determine the best management strategy for patients with stable ischemic heart disease (SIHD), ...

6. An Extension Study to Evaluate the Long-Term Safety and Tolerability of NEOD001 for Treatment of People with Light Chain Amyloidosis - Mayo Clinic

   The purpose of this study is to provide additional treatment with NEOD001 and evaluate long term safety and tolerability for patients wih light chain ...

7. National Biological Sample and Data Repository for Pulmonary Arterial Hypertension - Mayo Clinic

   The purpose of this study is to establish a collection, termed biorepository or biobank, of samples as well as both clinical and genetic data from patients with ...

8. A Study to investigate efficacy and safety of teplizumab compared with placebo in participants 1 to 25 years of age with Stage 3 Type 1 Diabetes - Mayo Clinic

   1 Diabetes (T1D). Participation eligibility. Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns ...

9. Development of an Evidenced-Based Tool for Prediction of Sudden Death in Patients With Non-Ischemic Cardiomyopathy - Mayo Clinic

   About this study. This study is an observational study to determine predictors of sudden cardiac death or appropriate ICD therapy in patients with ...

10. Extension Study of Mavacamten (MYK-461) in Adults With Symptomatic Obstructive Hypertrophic Cardiomyopathy Previously Enrolled in PIONEER - Mayo Clinic

    About this study. This is a multicenter open-label study of the administration of mavacamten in participants with symptomatic obstructive HCM (oHCM) who ...