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  1. A Study of Belantamab Mafodotin (GSK2857916) in Multiple Myeloma Participants With Normal and Impaired Renal Function - Mayo Clinic

    Belantamab mafodotin (GSK2857916) is an antibody-drug conjugate (ADC) containing humanized anti- B-cell maturation antigen (BCMA) monoclonal antibody (mAb).

  2. Oxaliplatin, Leucovorin Calcium, and Fluorouracil with or without Celecoxib in Treating Patients with Stage III Colon Cancer Previously Treated with Surgery - Mayo Clinic

    Celecoxib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. It is not yet known whether giving oxaliplatin, leucovorin ...

  3. 24-Week Study to Assess the PD, Safety, Tolerability, and PK of GLM101 in Adults With PMM2-CDG - Mayo Clinic

    The purpose of this study is to evaluate changes in coagulation and antithrombosis factors in adult participants with PMM2-CDG after 24 weeks of dosing.

  4. Clinical Trials - Loncastuximab Tesirine in WM

    Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and ...

  5. A Phase 3 Study to Evaluate Efficacy and Safety of Masitinib in Comparison to Sunitinib in Patients with Gastrointestinal Stromal Tumour After Progression with Imatinib - Mayo Clinic

    A Phase 3 Study to Evaluate Efficacy and Safety of Masitinib in Comparison to Sunitinib in Patients with Gastrointestinal Stromal Tumour After Progression with ...

  6. A Study to Analyze SAR442168 in Participants with Nonrelapsing Secondary Progressive Multiple Sclerosis - Mayo Clinic

    This study aims to determine the efficacy of SAR442168 compared to placebo in delaying disability progression in NRSPMS and on clinical endpoints, MRI lesions, ...

  7. The Rhythm Evaluation for AntiCoagulaTion With Continuous Monitoring of Atrial Fibrillation - Mayo Clinic

    About this study. The purpose of this study is to compare the current Standard Of Care (SOC) of continuous Direct Oral Anticoagulation (DOAC) use versus ...

  8. Efficacy and safety of subcutaneous dupilumab in participants with asthma/asthmatic wheeze aged 2 to <6 years - Mayo Clinic

    This study is a placebo-controlled, double-blind, randomized trail enrolling children aged 2 to <6 years old with uncontrolled asthma and/or recurrent severe ...

  9. A Study to Evaluate the Safety, Tolerability and Metabolism of BIIB105 in Subjects with Amyotrophic Lateral Sclerosis - Mayo Clinic

    The primary objective is to evaluate the safety and tolerability of BIIB105 in participants with amyotrophic lateral sclerosis (ALS) or poly-CAG expansion ( ...

  10. A Study to Evaluate M7824 with Concurrent Chemoradiation (cCRT) in Unresectable Stage III Non-small Cell Lung Cancer (NSCLC) - Mayo Clinic

    The primary purpose of this study is to evaluate safety and effectiveness in participants treated with concomitant chemoradiation therapy (cCRT) plus M7824 ...