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1. Vedolizumab IV in Pediatric Participants With Ulcerative Colitis or Crohn's Disease - Mayo Clinic

   Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and ...

2. Dose-finding Study of QGE031 as add-on Therapy to Evaluate Efficacy and Safety in Patients With CSU - Mayo Clinic

   This is a placebo and active-controlled phase 2b dose-finding study to evaluate efficacy and safety of QGE031 monthly subcutaneous injections as add-on therapy ...

3. A Single Patient Treatment Plan with Autologous Mesenchymal Stromal Cell Coated Fistula Plug in a Single Patient with Persistent Pouch-Vaginal Fistula - Mayo Clinic

   The purpose of this treatment plan is to use a treatment option only being used within a phase 1 research trial using an autologous mesenchymal stromal cell ( ...

4. Development and Validation of Newborn Screening Assays to Measure Biomarkers and Enzyme Levels in Biological Samples from Patients with a Lysosomal Storage Disorder and Their Relatives - Mayo Clinic

   The purpose of this study is to validate and evaluate several diagnostic tests in whole blood dried on filter paper (dried blood spots, DBS), the typical ...

5. A Study to Investigate the Effectiveness and Safety of Fenfluramine Hydrochloride as an Adjunctive Therapy in Children and Adults With Lennox-Gastaut Syndrome - Mayo Clinic

   This is a two-part, multicenter, double-blind, parallel-group, placebo controlled study to evaluate the effect of ZX008 when used as adjunctive therapy for the ...

6. Effects of Ischemia and Hypoxia on Exercise Tolerance and the Development of Quadriceps Fatigue in Men and Women - Mayo Clinic

   About this study. The goal of this study is to determine how neuromuscular fatigue in exercising muscle is influenced by local vs. global oxygen deficit.

7. Smartphone Twelve Lead Electrocardiogram Utility In ST-Elevation Myocardial Infarction - Mayo Clinic

   Is the Smartphone ECG (electrocardiogram) an acceptable replacement for a standard ECG in the identification of STEMI (ST Elevation Myocardial Infarction).

8. Horng H. Chen, M.D. - Mayo Clinic Faculty Profiles

   His research focuses on cardiorenal dysfunction and heart failure together with novel natriuretic peptide therapeutics in the syndrome of heart failure. Focus ...

9. A Study Evaluating the Use of Thalamic Deep Brain Stimulation (DBS) in the Treatment of Tremor - Mayo Clinic

   The purpose of this study is to directly compare the predictability of tremor reduction between two thalamic Deep Brain Stimulation (DBS) strategies.

10. Mepivacaine Versus Bupivacaine Onset Time in Ultrasound-guided Ankle Blocks - Mayo Clinic

    About this study. The purpose of this research is to determine if both local anesthetics are similar in their onset of sensory block to assess the ...