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  1. A Study to Evaluate the Safety and Effectiveness of OMS721 in Patients with Immunoglobulin A (IgA) Nephropathy - Mayo Clinic

    The purpose of this study is to evaluate the safety and effectiveness of OMS721 in patients with IgA nephropathy. The study will assess proteinuria by 24-hour ...

  2. A Study to Investigate the Safety and Effectiveness of FE 999049 in Controlled Ovarian Stimulation in Women Aged 35-42 Years Old - Mayo Clinic

    Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and ...

  3. A Study to Evaluate the Combination of Binimetinib and Palbociclib in Treating Patients with KRAS and NRAS Mutant Metastatic or Unresectable Colorectal Cancer - Mayo Clinic

    Binimetinib and palbociclib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, such as TAS- ...

  4. A Study to Evaluate Whether Macitentan is an Effective and Safe Treatment for Patients With Heart Failure With Preserved Ejection Fraction and Pulmonary Vascular Disease - Mayo Clinic

    The primary objective is to evaluate whether macitentan 10 mg reduces N-terminal pro-brain natriuretic peptide (NT-pro-BNP) as compared to placebo in these ...

  5. Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial - Mayo Clinic

    About this study. Carotid revascularization for primary prevention of stroke (CREST-2) is two independent multicenter, randomized controlled trials of ...

  6. Publications - Peter A. Noseworthy, M.D., M.B.A. - Mayo Clinic

    Sang P, Adel F, Maheshwari A, Mangold K, Attia Z, Cummings P, Davidge-Pitts C, Lopez-Jimenez F, Friedman P, Noseworthy P. Artificial Intelligence Evaluation of ...

  7. Erlotinib Hydrochloride and Cabozantinib-s-Malate Alone or In Combination as Second or Third Line Therapy in Treating Patients With Stage IV Non-Small Cell Lung Cancer - Mayo Clinic

    Erlotinib Hydrochloride and Cabozantinib-s-Malate Alone or In Combination as Second or Third Line Therapy in Treating Patients With Stage IV Non-Small Cell Lung ...

  8. VenusP-Valve Pivotal Study (PROTEUS STUDY) - Mayo Clinic

    The objective of this study is to evaluate the safety and effectiveness of the VenusP-ValveTM System in patients with native right ventricular outflow tract ( ...

  9. Oxaliplatin, Leucovorin Calcium, and Fluorouracil With or Without Bevacizumab in Treating Patients Who Have Undergone Surgery for Stage II Colon Cancer - Mayo Clinic

    About this study. This randomized phase III trial studies oxaliplatin, leucovorin calcium, fluorouracil, and bevacizumab to see how well they work compared ...

  10. Federalwide Assurance (FWA) - Mayo Clinic Research

    Institutional Review Board at Mayo Clinic: Federalwide Assurance outlines principles to protect the rights and welfare of research subjects.