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  1. Sorafenib for Hepatopulmonary Syndrome - Mayo Clinic

    About this study. The main purpose of this clinical trial is to determine the safety and effects of the study drug, sorafenib, in adults diagnosed with ...

  2. A Study to Measure the Connection of Cause and Effect in Muscle Contraction, and Changes Caused by Aging - Mayo Clinic

    The purpose of this study is to learn about and measure changes in muscle contraction that happen as healthy people age. The connection between electrical ...

  3. First-in-Human Study of KO-947 in Non-Hematological Malignancies - Mayo Clinic

    If an MTD cannot be identified, a recommended phase 2 dose (RP2D) will be determined. In addition, two tumor specific extension cohorts may be conducted to ...

  4. Feasibility of a Standardized Video for Patient Education and as a Decision Aid on Code Status for Patients in the Emergency Department Pending Admission to the Hospital - Mayo Clinic

    About this study. The researchers hypothesize that patients and their families will be comfortable watching standardized CPR informational videos and that ...

  5. A Study to Evaluate Sacubitril-Valsartan for Left Ventricular Reverse Remodeling in Adults with Congenital Heart Abnormality - Mayo Clinic

    The purpose of this study is to determine the optimal medical therapy to improve left ventricular (LV) function. Improvement in LV function has the potential to ...

  6. A Study of a Comprehensive, Holistic Approach to Sedation, Pain, Delirium, Early Mobilization, and Family Engagement in the Pediatric Intensive Care Unit - Mayo Clinic

    The frequency and length of education and training sessions will also be recorded, and PICU patient charts (electronic health records) will be reviewed to ...

  7. A Study to Evaluate Individualized Lifestyle Intervention for Obesity Management Based on Obesity Phenotypes - Mayo Clinic

    The purpose of this study is to define an "individualized diet" approach based on obesity related phenotypes (pathophysiology obesity classification), which ...

  8. Respiratory Failure Clinical Trials - Mayo Clinic Research

    The purpose of this study is to determine the impact of opioid administration on diaphragm muscle forces during resting breathing and during higher force ...

  9. A Study to Evaluate Collecting of Health Related Quality of Life Data in Newly Diagnosed AL Amyloidosis Patients - Mayo Clinic

    The purpose of this study is to evaluate the usefulness of collecting health related quality of life data on newly diagnosed AL amyloidosis patients.

  10. A Study Comparing the Addition of Structured Psychosocial Care versus Standard of Care to the Treatment of Patients with Inflammatory Bowel Disease - Mayo Clinic

    Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and ...