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  1. Ibrutinib and Rituximab Compared With Fludarabine Phosphate, Cyclophosphamide, and Rituximab in Treating Patients With Untreated Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma - Mayo Clinic

    Ibrutinib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, such as fludarabine phosphate ...

  2. A Study of the Relationship Between Infliximab Levels and the Rate of Colectomies in Patients who have Ulcerative Colitis - Mayo Clinic

    The purpose of this study is to assess if infliximab drug levels in patients who have Ulcerative Colitis predict the risk of needing a colectomy. Additionally, ...

  3. A Study to Evaluate the Efficacy and Safety of Lenalidomide as Maintenance Therapy for Patients With B-Cell Chronic Lymphocytic Leukemia (CLL) Following Second Line Therapy - Mayo Clinic

    The purpose of this study is to determine if lenalidomide (Revlimid®) is safe and effective as a maintenance therapy at improving further the quality of the ...

  4. Study to Evaluate the Efficacy and Safety of MEDI9929 (AMG 157) in Adult Subjects With Inadequately Controlled, Severe Asthma - Mayo Clinic

    The primary objective of the study is to evaluate the effect of 3 dose levels of MEDI9929 (AMG 157) on asthma exacerbations in adult subjects with inadequately ...

  5. Biophilic Office Design Study - Clinical Trials

    This study aims to measure the effects of biophilic visual features and acoustic features on office worker's mood and connectedness to nature, stress levels, ...

  6. A Study Comparing the Effectiveness and Safety of Combining Three versus Two Oral Treatments for the Initial Therapy of Patients who have Newly Diagnosed Hypertension of the Pulmonary Artery - Mayo Clinic

    The purpose of this study is to compare the effectiveness and safety of three (macitentan, tadalafil, and selexipag) versus two (macitentan and tadalafil) oral ...

  7. Regional Prophylactic Vancomycin With Restricted Tourniquet Time in Primary Total Knee Replacement - Mayo Clinic

    The purpose of this study is to determine whether or not giving a lower dose of antibiotics (Vancomycin) in the area where it is needed (the knee joint) is more ...

  8. C. Albicans during Early Life Predisposes Individuals to Atopy - Mayo Clinic

    The purpose of this study is to evaluate the contribution of C. albicans to dysbiotic microbial communities of mucosal tissues in pediatric populations.

  9. A Study of Napabucasin Plus Nab-Paclitaxel With Gemcitabine in Adult Patients With Metastatic Pancreatic Adenocarcinoma - Mayo Clinic

    Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and ...

  10. Detection of Circulating Biomarkers (Circulating Tumor Cells and Circulating Tumor DNA) in Patients with Head and Neck Carcinoma following Surgical Intervention - Mayo Clinic

    The goal of this research study is to evaluate the impact of surgical interventions on circulating biomarker dynamics and establish their prognostic role in ...