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  1. A Study of the Effect of Ezogabine on Motor Neuron Excitability in Patients with Amyotrophic Lateral Sclerosis - Mayo Clinic

    The purpose of this study is to evaluate the effect of retigabine dosages on motor neuron activity in people with Amyotrophic Lateral Sclerosis (ALS).

  2. Safety and Efficacy Study of the Medtronic CoreValve® System in the Treatment of Severe, Symptomatic Aortic Stenosis in Intermediate Risk Subjects Who Need Aortic Valve Replacement (SURTAVI). - Mayo Clinic

    Single Arm: The purpose of this trial is to evaluate the safety and effectiveness of transcatheter aortic valve implementation (TAVI) in patients with sever ...

  3. A Study to Evaluate Volumetric Laser Endomicroscopy with Intelligent Real-time Image Segmentation (IRIS) - Mayo Clinic

    About this study. The purpose of this study is to examine how IRIS (Intelligent Real-time Image Segmentation) affects biopsy patterns in VLE (Volumetric ...

  4. Phase ll Study of Pirfenidone in Patients With RAILD - Mayo Clinic

    The purpose of this study is to to assess the safety and tolerability of pirfenidone 2403 mg/day for the treatment of RA-associated interstitial lung disease.

  5. A Study to See if MPI SPECT Phase Analysis Can Detect Varying Levels of Changes in Heart Rhythm Patterns - Mayo Clinic

    The purpose of this study is to determine if MPI SPECT phase analysis can detect varying degrees of abnormal heart rhythm between patients with normal coronary ...

  6. A Study to Evaluate Whether or Not Selexipag is Effective and Safe in Patients with Chronic Thromboembolic Pulmonary Hypertension when the Disease is Inoperable or Persistent/Recurrent After Surgery - Mayo Clinic

    About this study. The primary objective of this study is to evaluate the effect of selexipag on pulmonary vascular resistance (PVR) versus placebo in ...

  7. A Study to Assess Symptoms in Working Age Stroke Survivors - Mayo Clinic

    The purposes of this study are to investigate the level of correspondence between the most severe and most bothersome symptoms, and to examine discordant ...

  8. A Study to Evaluate the Effectiveness and Safety of Ravulizumab in Adult Participants with Neuromyelitis Optica Spectrum Disorder - Mayo Clinic

    Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and ...

  9. A Study Whether Routine Use of Postoperative Belladonna and Opium Suppositories in Vaginal Surgery Improves Pain Control - Mayo Clinic

    The purpose of this study is to determine whether the routine use of belladonna and opium suppositories will improve pain control following vaginal surgery.

  10. Mindful Breathing Awareness Through Pursed-Lip Breathing Training - Mayo Clinic

    To establish the feasibility of a tool that monitors and motivates people with COPD to complete training in mindful pursed-lip breathing to enhance pulmonary ...