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  1. A Randomized Trial of Pembrolizumab & Radiotherapy Versus Radiotherapy in High-Risk Soft Tissue Sarcoma of the Extremity - Mayo Clinic

    About this study. This is an open-label, multi-institutional phase II randomized study comparing neoadjuvant radiotherapy followed by surgical resection to ...

  2. Contrast-enhanced rectal photon-counting detector CT for the local staging of rectal cancer - Mayo Clinic

    About this study. The purpose of this study is to examine the capability of contrast-enhanced pelvic PCD-CT for local staging of rectal cancer, ...

  3. Pasireotide LAR in Severe Polycystic Liver Disease - Mayo Clinic

    The purpose of this study is to compare SOM230 treatment to placebo. The investigators will also assess the efficacy and safety of SOM230 in reducing total ...

  4. Long-term Safety and Tolerability of Atacicept (Long-term Follow-Up of Patients Who Participated in ADDRESS II) - Mayo Clinic

    About this study. This is a multicenter, double-blind, Phase 2b, long-term extension (LTE) to the ADDRESS II core trial (EMR 700461-023) (NCT01972568), ...

  5. Study to Evaluate the Effectiveness and Safety of Nefecon in Patients With Primary IgA (Immunoglobulin A) Nephropathy - Mayo Clinic

    Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and ...

  6. A Study Evaluating the Safety and Effectiveness of the PulseRider® Aneurysm Neck Reconstruction Device Used in Conjunction With Endovascular Coil Embolization in the Treatment of Wide-Neck Bifurcation Intracranial Aneurysm - Mayo Clinic

    This is a prospective, multi-center, non-randomized clinical evaluation utilizing the PulseRider® Aneurysm Neck Reconstruction Device. Participation eligibility.

  7. Ultrasound Assessment of Weightbearing and Non-Weightbearing Meniscal Protrusion - Mayo Clinic

    The purpose of this study is to determine the intra-rater and inter-rater reliability of US measurements of meniscal protrusion with and without weight bearing.

  8. A Study of Subcutaneous versus Subpectoral Placement for 2-Staged Implant-Based Breast Reconstruction - Mayo Clinic

    The purpose of this study is to learn whether there are differences in the outcome between placing the tissue expander above or below the chest muscle in women ...

  9. Effect of Topical Phenylephrine 2.5% on EVP in Normal Human Eyes - Mayo Clinic

    Phenylephrine hydrochloride ophthalmic solution is an alpha-1 adrenergic receptor agonist commonly used topically for dilation prior to ocular fundus ...

  10. A Study to Assess Biomarkers in Patients with Osteonecrosis of the Femoral Head - Mayo Clinic

    The purposes of this study is to isolate RNA from bone tissues from ONFH and osteoarthritis (OA) femoral heads and perform RNA sequencing to measure gene ...