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  1. Transapical and Transfemoral TAVR, Two Different Patient Populations with Possible Similar Clinical and Cardiac Mechanics Outcomes

    About this study. Compare transapical and transfemoral TAVR as regards clinical outcomes (both beneficial including improvement in heart failure class ...

  2. Patients with Inflammatory Bowel Disease (IBD) are at Increased Risk for Colorectal Cancer and Early Dysplasia - Mayo Clinic

    Map and compare the neoplasia-associated epigenetic field in IBD-CRN, sporadic CRN and controls. Measure sensitivity of DNA methylation for the detection of ...

  3. Radiation Therapy with or without Cetuximab in Treating Patients Who Have Undergone Surgery for Locally Advanced Head and Neck Cancer - Mayo Clinic

    Monoclonal antibodies, such as cetuximab, can block tumor growth in different ways. Some block the ability of tumor cells to grow and spread. Others find tumor ...

  4. A Study to Evaluate the Effect of ALLN-177 in Reducing Urinary Oxalate in Patients with Hyperoxaluria and Kidney Stones - Mayo Clinic

    The purpose of this study is to evaluate the safety, tolerability, and effectiveness of different doses of ALLN 177 for reducing urinary oxalate excretion in ...

  5. Study to Evaluate Implantable Tibial Neuromodulation - Mayo Clinic

    The purpose of this study is to assess the safety and effectiveness of tibial neuromodulation using the Medtronic Tibial Neuromodulation (TNM) system by ...

  6. 3,4-diaminopyridine (3,4-DAP) use in Patients with Orthostatic Hypotension and Postural Tachycardia Syndrome - Mayo Clinic

    Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and ...

  7. Normal and Dyssynergic Defecation - Mayo Clinic

    The purpose of this study will compare respiratory functions, abdominal wall motion, and anorectal pressures in healthy controls and patients with dyssynergic ...

  8. Tricuspid Valve Disease KCCQ Validation - Mayo Clinic

    The purpose of this study is to use patient interviews and qualitative research methods to determine the gaps in the current KCCQ in patients with severe ...

  9. Feasibility Trial Using Imaging and Biochemical Technologies to Measure Knee Cartilage Composition in Acute ACL Injury - Mayo Clinic

    This study will evaluate the bio-mechanical and biochemical abnormalities in acute ACL-injured knees over time. Data will be collected through advanced ...

  10. Study of Incidence of Respiratory Tract AEs in Patients Treated With Tyvaso® Compared to Other FDA Approved PAH Therapies - Mayo Clinic

    A surveillance of respiratory tract related adverse events in patients treated with Tyvaso® (treprostinil) Inhalation Solution versus other FDA approved ...