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  1. A Study of Diabetes-associated Epigenomic Signatures in Humans - Mayo Clinic

    About this study. The obectives of this study are to identify insulin resistance (IR)-specific chromatin signatures in mature adipocytes and myotubes, ...

  2. A Open Label Study of the Efficacy and Safety of PD0332991 a Selective Inhibitor of the Cyclin Dependent Kinases 4 and 6 in Patients With Recurrent Ovarian Cancer Demonstrating Rb-proficiency and Low p16 Expression - Mayo Clinic

    A Open Label Study of the Efficacy and Safety of PD0332991 a Selective Inhibitor of the Cyclin Dependent Kinases 4 and 6 in Patients With Recurrent Ovarian ...

  3. A Study to Test How Muscle Tissue Differs Between People - Mayo Clinic

    Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and ...

  4. Safety Study of Mocetinostat in Combination With Azacitidine in Subjects With MDS - Mayo Clinic

    Mocetinostat is an orally administered histone deacetylase (HDAC) inhibitor. Azacitidine is a hypomethylating agent (HMA) used to treat MDS. In this study, ...

  5. Testing the Use of Chemotherapy After Surgery for High-Risk Pancreatic Neuroendocrine Tumors - Mayo Clinic

    Chemotherapy drugs, such as capecitabine and temozolomide, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping ...

  6. Avelumab With Binimetinib, Sacituzumab Govitecan, or Liposomal Doxorubicin in Treating Patients With Stage IV or Unresectable, Recurrent Triple Negative Breast Cancer - Mayo Clinic

    Avelumab With Binimetinib, Sacituzumab Govitecan, or Liposomal Doxorubicin in Treating Patients With Stage IV or Unresectable, Recurrent Triple Negative Breast ...

  7. A Study of AdAPT-001 in Subjects With Sarcoma and Refractory Solid Tumors - Mayo Clinic

    The purpose of this study is to determine the safety and tolerability profile of a single dose of AdAPT-001 in subjects with advanced solid tumors that have ...

  8. A Study of NGM282 When Given to Subjects with Functional Constipation and to Healthy Individuals - Mayo Clinic

    The purpose of this study is to determine the effect of NGM282 on colonic transit, bile acid homeostasis, and fecal fat in subjects with functional constipation ...

  9. A Study to Evaluate Chemotherapy-Induced Nausea in Breast Cancer Patients - Mayo Clinic

    The long-term goal of this study is to alleviate the occurrence of CIN and fatigue and to improve chemotherapy treatment outcomes. The identification of ...

  10. Safety Study of VAL-083 in Patients with Recurrent Malignant Glioma - Mayo Clinic

    Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and ...