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  1. Prophylactic Ethanol Lock Therapy (ELT) in Patients on Home Parenteral Nutrition - Mayo Clinic

    This study is being implemented to identify the role of prophylactic use of ethanol lock in adult patients on home parenteral nutrition (HPN). Central catheter ...

  2. A Open Label Study of the Efficacy and Safety of PD0332991 a Selective Inhibitor of the Cyclin Dependent Kinases 4 and 6 in Patients With Recurrent Ovarian Cancer Demonstrating Rb-proficiency and Low p16 Expression - Mayo Clinic

    The purpose of this study is to obtain an estimate of the biochemical response rate as determined by CA125 response using the Gynecologic Cancer Intergroup ( ...

  3. Safety Study of VAL-083 in Patients with Recurrent Malignant Glioma - Mayo Clinic

    Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and ...

  4. A Study of Diabetes-associated Epigenomic Signatures in Humans - Mayo Clinic

    About this study. The obectives of this study are to identify insulin resistance (IR)-specific chromatin signatures in mature adipocytes and myotubes, ...

  5. Defibrotide for Patients with Hepatic Veno-occlusive Disease: A Treatment IND Study - Mayo Clinic

    Single arm, open-label study to provide Defibrotide to patients diagnosed with VOD. Defibrotide is no longer available though the Emergency Use IND mechanism ( ...

  6. A Study to Evaluate the Safety, Tolerability, and Effectiveness of Cilofexor in Non-Cirrhotic Adults With Primary Sclerosing Cholangitis - Mayo Clinic

    The primary purpose of this study is to evaluate whether cilofexor reduces the risk of fibrosis progression among non-cirrhotic adults with primary sclerosing ...

  7. A Global Phase III Study Of Rilvegostomig Or Pembrolizumab Plus Chemotherapy For First-Line Treatment Of Metastatic Non-squamous NSCLC - Mayo Clinic

    About this study. The purpose of ARTEMIDE-Lung03 is to evaluate the efficacy and safety of rilvegostomig compared to pembrolizumab, both in combination with ...

  8. Trials Evaluating Oral Full-Spectrum Microbiota™ (CP101) in Subjects with Recurrence of Clostridium difficile Infection - Mayo Clinic

    The purpose of this study is to evaluate the safety and effectiveness of CP101 treatment in adults who had a Clostridum difficile Infection (CDI) recurrence ...

  9. A Study to Evaluate Imaging in Non-urgent, Symptomatic and Asymptomatic Individuals with E-cigarette or Vaping Lung Injury - Mayo Clinic

    The purpose of this study is to evaluate the hypothesis that e-cigarette use, or vaping, product-associated lung injury (EVALI) is underdiagnosed and can be ...

  10. Phase 2 Study of VGT-309 in Lung Cancer - Mayo Clinic

    The purpose of this study is to evaluate safety and efficacy of VGT-309 to identify cancer in up to 40 subjects undergoing lung cancer surgery. Participation ...