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1. Testing Nivolumab and Ipilimumab With Short-Course Radiation in Advanced Rectal Cancer - Mayo Clinic

   Radiation therapy uses high energy x-rays to kill tumor cells and shrink tumors. Giving nivolumab, ipilimumab, and radiation therapy may kill more cancer cells.

2. WEE1 Inhibitor AZD1775 With or Without Cytarabine in Treating Patients With Advanced Acute Myeloid Leukemia or Myelodysplastic Syndrome - Mayo Clinic

   WEE1 inhibitor AZD1775 may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, such as ...

3. A Study to Test the Addition of Nivolumab to Chemotherapy to Treat Soft Tissue Sarcoma - Mayo Clinic

   Nivolumab works through the body's immune system to help the immune system act against tumor cells. Chemotherapy drugs, such as paclitaxel, work in different ...

4. Safety and Preliminary Efficacy of OBT076 in Recurrent/​Metastatic CD205+ Solid Tumors - Mayo Clinic

   Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and ...

5. A Study to Evaluate Fostamatinib Disodium to Treat Warm Antibody Autoimmune Hemolytic Anemia - Mayo Clinic

   The primary objective of this study is to assess the effectiveness of fostamatinib in subjects with warm antibody autoimmune hemolytic anemia (wAIHA).

6. A Study to Evaluate the Effectiveness and Safety of Lanadelumab for Prevention Against Acute Attacks of Non-histaminergic Angioedema in Adolescents and Adults - Mayo Clinic

   The purpose of this study is to evaluate the safety and effectiveness of repeated subcutaneous (SC) administrations of Lanadelumab in preventing angioedema ...

7. Study Evaluating the Safety and Efficacy of Rap-219 in Adult Participants With Refractory Focal Epilepsy - Mayo Clinic

   The purpose of this study is to demonstrate that RAP-219 is effective in reducing frequency of RNSrecorded long episodes in participants with focal onset ...

8. Nilotinib and Combination Chemotherapy in Treating Patients with Newly Diagnosed Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia or Blastic Phase Chronic Myelogenous Leukemia - Mayo Clinic

   About this study. In this study researchers want to find out more about the side effects of a new drug for Philadelphia chromosome-positive (Ph+) acute ...

9. Define in Humans With Compensated CHF and Renal Dysfunction, the Modulating Action of Chronic AT1 Receptor Blockade in Addition to ACE Inhibition on Cardiorenal and Humoral Function - Mayo Clinic

   To advance our understanding of the mechanisms of human cardiorenal syndrome with emphasis upon the interaction of diuretic therapy and the renal-angiotensin- ...

10. Nesiritide in Resistant Hypertension - Clinical Trials

    About this study. The aim of this study is two fold: First the investigators want to determine the safe and most effective dose of subcutaneous (SQ) BNP in ...