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1. Echocardiographic Measures of Pulmonary Vascular Distensibility and Effects on Lung Diffusing Capacity - Mayo Clinic

   The purpose of this study is to determine if the change in pulmonary vascular compliance with positional changes (upright, supine, and Trendelenburg position) ...

2. S1406 A Phase II Study of Irinotecan and Cetuximab with or without Vemurafenib in BRAF Mutant Metastatic Colorectal Cancer - Mayo Clinic

   Irinotecan hydrochloride and vemurafenib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Monoclonal antibodies, such ...

3. A Study to Analyze Intracerebral Hemorrhage Hematoma - Mayo Clinic

   The purpose of this study is to to take the usual waste material from the removal of hematoma and apply an array of -Omics approaches (including for example ...

4. Ph1b/2 Dose-Escalation Study of Entinostat With Pembrolizumab in NSCLC With Expansion Cohorts in NSCLC, Melanoma, and Colorectal Cancer - Mayo Clinic

   Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and ...

5. A Study Evaluating Respiratory Causes Impacting Pilot Performance - Mayo Clinic

   The purpose of Task 2, entitled "The Cognitive Performance Cost of Increased Work of Breathing: Phase II," is to determine the impact of inspiratory and ...

6. Ph 3 Trial of Blinatumomab vs Investigator's Choice of Chemotherapy in Patients with Relapsed or Refractory ALL - Mayo Clinic

   Adult subjects with R/R B-precursor ALL will be randomized in a 2:1 ratio to receive blinatumomab or treatment with investigator choice of 1 of 4 protocol ...

7. Filgotinib in the Induction and Maintenance of Remission in Adults With Moderately to Severely Active Crohn's Disease - Mayo Clinic

   Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and ...

8. MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial) - Mayo Clinic

   The marker testing in this study will let doctors know if they can match patients with a treatment study (myeloMATCH clinical trial) that tests treatment for ...

9. Study of Veltuzumab and 90Y-Epratuzumab in Relapsed/Refractory, Aggressive NHL - Mayo Clinic

   The goal of this study is to evaluate a new approach to immunotherapy in NHL by combining two antibodies, veltuzumab and epratuzumab. For treatment, epratuzumab ...

10. A Study to Establish An Integrated Biomarker Panel for COVID-19 Infection Risk and Severity Prediction - Mayo Clinic

    Aim 2: Investigate if mutations or polymorphisms in genes (CXCR6, ACE2 and SLC6A20) linked to SARS-CoV-2 correlates with the three clinical patient outcome ...