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  1. A Study of Fresolimumab in Patients with Steroid-Resistant Primary Focal Segmental Glomerulosclerosis (FSGS) - Mayo Clinic

    To evaluate fresolimumab dose-dependent reduction in proteinuria; To compare the change in renal function (estimated glomerular filtration rate [eGFR]) in ...

  2. An Open-Label Extension Study of Palovarotene to Treat Preosseous Flare-ups in FOP Subjects - Mayo Clinic

    Fibrodysplasia Ossificans Progressiva (FOP) is a rare, severely disabling disease characterized by painful, recurrent episodes of soft tissue swelling (flare- ...

  3. Cardiac Resynchronization and Iodine Meta-Iodobenzylguanidine (MIBG) Imaging - Mayo Clinic

    Congestive heart failure (CHF) affects nearly 5 million Americans and claims more than 300,000 lives annually. A primary pathophysiologic mechanism in this ...

  4. Estimating Reference Change Value for Tests of Platelet Function - Mayo Clinic

    The purpose of this study is to define the change or “delta” in platelet function tests that represents a significant change in patient condition, to facilitate ...

  5. Survival and Other Outcomes in Parkinson Disease: Clinical and Genetic

    The purpose of this study is to answer the question, "Do baseline clinical and/or genetic factors predict survival, and other outcomes (e.g., dementia, ...

  6. Open-Label Study of the Long Term Safety of Pirfenidone in Patients With Idiopathic Pulmonary Fibrosis (IPF) - Mayo Clinic

    About this study. This is an open-label, multi-center, extension study for patients with IPF who complete a qualifying InterMune clinical trial of ...

  7. Quantitative Transmission Imaging Evaluation With MRI as Supplemental Screening to Mammography in Patients With High Lifetime Risk of Breast Cancer - Mayo Clinic

    The purpose of this study is to perform a prospective feasibility study with a goal of n=25 to compare the screening performance of QTI to MRI and other ...

  8. Study of Safety of Foradil in Patients with Persistent Asthma - Mayo Clinic

    Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and ...

  9. A Study of Donated Alloantigen Reactive Regulatory T Cells for Reducing or Discontinuing Immune System Suppression in Liver Transplant Patients - Mayo Clinic

    About this study. This research study is for liver transplant recipients and their respective living donors. The purpose of this study is to see if it is ...

  10. A Study to Evaluate RNA Transcriptomics for Predicting Allograft Failure or Rejection - Mayo Clinic

    The primary purpose of this study is to evaluate the feasibility of analysis of RNA transcripts from EVs sampled from the coronary sinus. Participation ...