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  1. IMC-F106C Regimen Versus Nivolumab Regimens in Previously Untreated Advanced Melanoma (PRISM-MEL-301) - Mayo Clinic

    Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and ...

  2. A Study of INCMGA00012 in Metastatic Merkel Cell Carcinoma - Mayo Clinic

    Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and ...

  3. Cardiotoxic Effects of Chemotherapy in Patients with Sarcomas - Mayo Clinic

    About this study. The purpose of this study is to determine if two-dimensional speckle tracking echocardiography (2D-STE) derived-strain can detect early ...

  4. PH 1 Study to Evaluate Safety and Tolerability of XmAb14045 in Patients With CD123-expressing Hematologic Malignancies - Mayo Clinic

    About this study. Primary Objectives 1. To determine the safety and tolerability profile of weekly IV dosing of XmAb14045 2. To identify the first dose MTD/ ...

  5. A Phase 1b/2 Safety and Tolerability of MEDI6469 in Combination With Therapeutic Immune Agents or Monoclonal Antibodies - Mayo Clinic

    Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and ...

  6. Study of the Efficacy, Safety, and Tolerability of Serlopitant for the Treatment of Refractory Chronic Cough - Mayo Clinic

    Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and ...

  7. Defibrotide for Patients with Hepatic Veno-occlusive Disease: A Treatment IND Study - Mayo Clinic

    Single arm, open-label study to provide Defibrotide to patients diagnosed with VOD. Defibrotide is no longer available though the Emergency Use IND mechanism ( ...

  8. Dose Escalation Study of mRNA-2752 for Intratumoral Injection to Participants in Advanced Malignancies - Mayo Clinic

    The purpose of this study is to assess the safety and tolerability of escalating intratumoral doses of mRNA-2752 in participants with relapsed/refractory solid ...

  9. A Study to Test How Effective and Safe GLPG1690 is for Subjects With Idiopathic Pulmonary Fibrosis (IPF) When Used Together With Standard Medical Treatment - Mayo Clinic

    The primary purpose of this study is to see how GLPG1690 works together with current standard treatment on lung function and IPF disease in general. The study ...

  10. Glembatumumab Vedotin in Treating Patients With Metastatic or Locally Recurrent Uveal Melanoma - Mayo Clinic

    About this study. This phase II trial studies how well glembatumumab vedotin works in treating patients with middle layer of the wall of the eye (uveal) ...