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1. Transfemoral Replacement of Aortic Valve With HLT MeriDIAN Valve Early Feasibility Trial - Mayo Clinic

   The purpose of this study is to evaluate the safety and performance of the HLT System in patients with severe aortic stenosis who present at High Risk for ...

2. Erismodegib and Lenalidomide After Stem Cell Transplant in Treating Patients With Multiple Myeloma - Mayo Clinic

   Erismodegib and lenalidomide may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth and may delay the recurrence of myeloma ...

3. A Study of Sotatercept for the Treatment of Pulmonary Arterial Hypertension - Mayo Clinic

   The purpose of this study is to evaluate the effect of sotatercept (ACE-011) in adults with Pulmonary Arterial Hypertension. Each eligible participant will ...

4. Erlotinib Hydrochloride and Cabozantinib-s-Malate Alone or In Combination as Second or Third Line Therapy in Treating Patients With Stage IV Non-Small Cell Lung Cancer - Mayo Clinic

   Erlotinib hydrochloride and cabozantinib-s-malate may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. It is not yet known ...

5. A Study of SC-006 in Subjects With Advanced Cancer - Mayo Clinic

   About this study. This is a multicenter, open-label, Phase 1 study in participants with colorectal cancer (CRC), and consists of Part A (dose regimen ...

6. A Study to Evaluate the Effectiveness and Safety of BG00011 in Participants with Idiopathic Pulmonary Fibrosis (SPIRIT) - Mayo Clinic

   The primary purpose of this study is to evaluate the effectiveness of BG00011 compared with placebo in participants with Idiopathic Pulmonary Fibrosis (IPF).

7. A Study of Rovalpituzumab Tesirine as Maintenance Therapy Following First-Line Platinum-Based Chemotherapy in Participants With Extensive Stage Small Cell Lung Cancer (MERU) - Mayo Clinic

   About this study. This is a Phase 3, randomized, double-blind, placebo-controlled, multinational, and multicenter study to evaluate the efficacy of ...

8. A Study of REACT in Subjects With Type 2 Diabetes Mellitus and Chronic Kidney Disease - Mayo Clinic

   The purpose of this study is to assess the safety and efficacy (including durability) of up to 2 REACT injections given 3 months (+30 days) apart and delivered ...

9. Efficacy and Safety of Tislelizumab in Combination With Fruquintinib in Participants With Selected Solid Tumors - Mayo Clinic

   The purpose of this research is to see how well fruquintinib works in combination with tislelizumab in participants with metastatic colorectal cancer (mCRC).

10. Dinaciclib, Bortezomib, and Dexamethasone in Treating Patients With Relapsed Multiple Myeloma - Mayo Clinic

    Dinaciclib and bortezomib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, such as ...