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  1. A Study to Evaluate the Effectiveness and Safety of Vibegron Administered Orally for 12 Weeks to Women with Irritable Bowel Syndrome - Mayo Clinic

    The purpose of this study is to evaluate the effectiveness and safety of vibegron, a beta-3 adrenergic receptor (β3-AR) agonist, in the treatment of pain ...

  2. A Phase I, Multi-Center, Open Label, Dose De-escalation and Expansion Study of Gemcitabine and Cisplatin with AG120 or Pemigatinib for Advanced Cholangiocarcinoma - Mayo Clinic

    Ivosidenib and pemigatinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Giving gemcitabine and cisplatin with ...

  3. A Double Blind, Randomized Controlled Study, Evaluating the Safety and Efficacy of RD2 Ver.02 For the Management of Anal Fistulas - Mayo Clinic

    The purpose of this study is to assess the safety of autologous RD2 Ver.02 as compared to a control for managing transsphincteric and intersphinsteric anal ...

  4. A Study to Evaluate Adjuvant Ado-Trastuzumab Emtansine (T-DM1) in HER2 Positive Breast Cancer - Mayo Clinic

    About this study. The purpose of this study is to evaluate an investigational drug as a possible treatment for breast cancer that is positive for the ...

  5. A Study of Obeticholic Acid Evaluating Clinical Outcomes in Patients with Primary Biliary Cirrhosis

    Primary biliary cirrhosis is a serious, life-threatening, bile acid related liver disease of unknown cause. Without treatment, it frequently progresses to liver ...

  6. Vaccine Therapy With Bevacizumab Versus Bevacizumab Alone in Treating Patients With Recurrent Glioblastoma Multiforme That Can Be Removed by Surgery - Mayo Clinic

    Vaccines consisting of heat shock protein-peptide complexes made from a person's own tumor tissue may help the body build an effective immune response to kill ...

  7. Abiraterone/Prednisone, Olaparib, or Abiraterone/Prednisone + Olaparib in Patients With Metastatic Castration-Resistant Prostate Cancer With DNA Repair Defects - Mayo Clinic

    This is a biomarker preselected, randomized, open-label, multicenter, phase II study in men with metastatic castration resistant prostate cancer (mCRPC).

  8. https://www.mayoclinic.org/~/media/0439A7376021433E8FB3180F95C8FF95

  9. Phase II Study Evaluating Combination Chemotherapy + Radiotherapy (RT) with Avelumab in Muscle Invasive Bladder Cancer - Mayo Clinic

    The purpose of this study is to evaluate the complete response rate of concurrent chemotherapy radiation treatment combined with avelumab for patients with ...

  10. Inclisiran for Participants With Atherosclerotic Cardiovascular Disease and Elevated Low-density Lipoprotein Cholesterol - Mayo Clinic

    This is a Phase III, placebo-controlled, double-blind, randomized study in participants with ASCVD and elevated LDL-C despite maximum tolerated dose of LDL-C ...