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  1. A Study Comparing the Safety of Tofacitinib versus Tumor Necrosis Factor Inhibitor in Patients with Rheumatoid Arthritis - Mayo Clinic

    Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and ...

  2. A Study of Iron Deficiency and Sleep Disruption in Children with Atopic Dermatitis - Mayo Clinic

    The purpose of this study is to determine if there is an association between atopic dermatitis and iron deficiency (low iron in the blood). We are also looking ...

  3. To Compare the Effects of Immediate-release Tacrolimus and Astagraf XL on Donor-Specific Antibody (DSA) Formation and the Development of Immune Activation (IA) in de Novo Kidney Transplant Recipients - Mayo Clinic

    About this study. This study will compare the incidence of a two-part composite endpoint consisting of de novo donor specific antibody (DSA) formation or a ...

  4. Study of ACTR087 in Combination With SEA-BCMA in Subjects With Relapsed or Refractory Multiple Myeloma - Mayo Clinic

    This is a phase 1, multi-center, single-arm, open-label study evaluating the safety, tolerability, and anti-myeloma activity of ACTR087 (an autologous T cell ...

  5. Semantic Dementia Clinical Trials - Mayo Clinic Research

    The purpose of this study is to develop and test the effectiveness of an investigational imaging technique called magnetic resonance elastography (MRE) to ...

  6. Efficacy and Safety Study of Lenalidomide Plus R-CHOP Chemotherapy Versus Placebo Plus R-CHOP Chemotherapy in Untreated ABC Type Diffuse Large B-cell Lymphoma - Mayo Clinic

    To evaluate the efficacy and safety of lenalidomide, rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone (R2-CHOP) chemotherapy versus placebo ...

  7. A Study of a Behavioral Model for Promoting Quality of Life and Successful Brain Aging - Mayo Clinic

    The purpose of this study is to assess an attention and emotion regulation intervention that systematically targets thoughts, emotions and behavior in order to ...

  8. A Study to Evaluate Induction Chemotherapy with ABVD Followed by Brentuximab Vedotin Consolidation in Previously-untreated, Non-bulky Stage I or II Hodgkin Lymphoma - Mayo Clinic

    Brentuximab vedotin is approved by the United States Food and Drug administration (FDA) for the treatment of Hodgkin lymphoma that has come back (relapsed). For ...

  9. Efficacy and Safety of Benralizumab in EGPA Compared to Mepolizumab - Mayo Clinic

    The purpose of this study is to evaluate the effectiveness and safety of Benralizumab compared to Mepolizumab to treat Eosinophilic Granulomatosis with ...

  10. Department of Molecular Pharmacology and Experimental Therapeutics Research - Affiliations

    Research activities within the Department of Molecular Pharmacology and Experimental Therapeutics are affiliated with several other Mayo Clinic research areas:.