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1. Exploring Mechanisms of Action and Resistance of Therapeutic Agents in Patients with B-cell Malignancies - Mayo Clinic

   This study is being performed to understand the causes of drug resistance and to improve the treatment options for patients diagnosed with B-cell cancers. We ...

2. A Study to Evaluate Oxygen Supplementation Duration to Assess Resolution of Acute Hypoxic Respiratory Failure - Mayo Clinic

   Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and ...

3. A Study of IMO-2125 in Combination With Ipilimumab Versus Ipilimumab Alone in Subjects With Anti-PD-1 Refractory Melanoma (ILLUMINATE-301) - Mayo Clinic

   The purpose of this study is to compare ipilimumab with and without IMO-2125 in advanced melanoma patients. Participation eligibility. Participant eligibility ...

4. Efficacy and Safety of Treatment With Alpelisib Plus Endocrine Therapy in Patients With HR+, HER2-negative aBC, With PIK3CA Mutations, Whose Disease Has Progressed on or After CDK 4/6 Treatment With an Aromatase Inhibitor (AI) or Fulvestrant - Mayo Clinic

   ... 6 Treatment With an Aromatase Inhibitor (AI) or Fulvestrant. Print details. Share; Facebook · Twitter. Overview; Participation eligibility; Participating Mayo ...

5. CTX131 in Relapsed/Refractory Hematologic Malignancies - Mayo Clinic

   The purpose of this study is to evaluate the safety, efficacy, pharmacokinetics (PK), and pharmacodynamic effects of CTX131 in adult study subjects with ...

6. In Clinical Trials - Mayo Clinic Research

   The purpose of this study is to assess the effectiveness and safety of Lubiprostone in pediatric patients, aged ≥ 6 years to < 18 years, diagnosed with ...

7. A Study to Create a Registry for Patients at High-Risk for Pancreatic Cancer - Mayo Clinic

   This study aims to facilitate discovery and validation of tests for early detection in subjects at high risk for pancreatic ductal adenocarcinoma (PDAC). and to ...

8. A Phase I Study of MSB2311 in Advanced Solid Tumors - Mayo Clinic

   Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and ...

9. A Global Phase III Study Of Rilvegostomig Or Pembrolizumab Plus Chemotherapy For First-Line Treatment Of Metastatic Non-squamous NSCLC - Mayo Clinic

   About this study. The purpose of ARTEMIDE-Lung03 is to evaluate the efficacy and safety of rilvegostomig compared to pembrolizumab, both in combination with ...

10. A Study to Assess the Antitumor Activity and Safety of IMAB362 in Combination With Nab-Paclitaxel and Gemcitabine (Nab-P + GEM) as First Line Treatment in Subjects With Claudin 18.2 Positive, Metastatic Pancreatic Adenocarcinoma - Mayo Clinic

    This study will also evaluate other anti-tumor effects, tumor markers and pharmacokinetics (PK) of zolbetuximab, Nab-P and GEM. Participation eligibility.