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  1. A Study to Evaluate Enfortumab Vedotin to Treat Metastatic Squamous Cell Carcinoma of the Penis - Mayo Clinic

    The purpose of this study is to estimate the best response of enfortumab vedotin treatment for patients with metastatic squamous cell carcinoma of the penis ( ...

  2. A Study to Evaluate the Impact on NASH with Fibrosis of Obeticholic Acid Treatment - Mayo Clinic

    The primary objectives of this study are to evaluate the effect of Obeticholic Acid treatment compared to placebo on 1) histological improvement and 2) liver- ...

  3. Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial - Mayo Clinic

    About this study. Carotid revascularization for primary prevention of stroke (CREST-2) is two independent multicenter, randomized controlled trials of ...

  4. A Phase 1/2 Study to Investigate Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of HMB-001 in Glanzmann Thrombasthenia - Mayo Clinic

    The purpose of this study is to Investigate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of HMB-001 in Participants with Glanzmann ...

  5. A Study To Investigate The Efficacy, Safety, And Pharmacokinetics Of Oral Rilzabrutinib Compared With Placebo In Participants 18 Years Of Age And Older With Warm Autoimmune Hemolytic Anemia - Mayo Clinic

    Following a 4-week screening period, eligible participants will be randomized in a 2:1 ratio to receive rilzabrutinib or placebo in primary analysis period (PAP) ...

  6. A Study to Evaluate Patisiran in Participants with Transthyretin Amyloidosis with Cardiomyopathy (ATTR Amyloidosis with Cardiomyopathy) - Mayo Clinic

    Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and ...

  7. Erlotinib Hydrochloride and Cabozantinib-s-Malate Alone or In Combination as Second or Third Line Therapy in Treating Patients With Stage IV Non-Small Cell Lung Cancer - Mayo Clinic

    Erlotinib Hydrochloride and Cabozantinib-s-Malate Alone or In Combination as Second or Third Line Therapy in Treating Patients With Stage IV Non-Small Cell Lung ...

  8. Ixazomib Plus Pomalidomide and Dexamethasone in Treating Patients with Relapsed or Relapsed/Refractory Multiple Myeloma - Mayo Clinic

    Giving ixazomib with pomalidomide and dexamethasone may be an effective treatment for relapsed or relapsed/refractory multiple myeloma. Participation ...

  9. A Study of a Therapeutic DNA Vaccine for Chronic Hepatitis C Virus (HCV) Infection - Mayo Clinic

    Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and ...

  10. A Study to Evaluate the Safety and Effectiveness of Metformin and Nelfinavir with Bortezomib in Patients with Relapsed and/or Refractory Multiple Myeloma - Mayo Clinic

    The purpose of this study is to assess the maximum tolerated dose (MTD) of administering metformin in combination with nelfinavir in patients with relapsed/ ...