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  1. Study to Evaluate the Safety, Pharmacokinetics and Clinical Benefit of FLU-IGIV in Hospitalized Patients with Serious Influenza A Infection

    The purpose of this study is to determine the optimal dose of FLU-IGIV based upon evaluation of safety and pharmacokinetics in hospitalized patients with ...

  2. Atezolizumab With or Without Cobimetinib in Treating Patients With Metastatic Bile Duct Cancer That Cannot Be Removed by Surgery or Gallbladder Cancer - Mayo Clinic

    Cobimetinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Giving atezolizumab with cobimetinib may work better at ...

  3. Tradipitant After GLP-1R Agonist In Healthy, Overweight, or Class I or II Obese Volunteers - Mayo Clinic

    The purpose of this study is to evaluate the effect of tradipitant relative to placebo on proportion of subjects with at least 1 vomiting episode per week ...

  4. Phase 2a Open-Label Pilot Study of VTX2735 in Recurrent Pericarditis - Mayo Clinic

    The purpose of this study is to evaluate the safety and tolerability of VTX2735 in participants with symptomatic recurrent pericarditis. Participation ...

  5. A Study to Investigate FE 999049 in the Treatment of Infertility in Women Aged 18-34 Years Old with Assisted Reproductive Technology - Mayo Clinic

    The purpose of this study is to investigate the safety and effectiveness of FE 999049 compared to placebo in women aged 18-34 years old. Participation ...

  6. EORTC-1709-BTG_CCTG-CE.8: A Study to Compare Marizomib in Combination with Standard Radiochemotherapy vs. Radiochemotherapy Alone in Patients with Newly- diagnosed Glioblastoma MIRAGE - Mayo Clinic

    The purpose of this study is to evaluate the safety and tolerability of marizomib in combination with Temozolomide-based radiochemotherapy versus standard ...

  7. SC16LD6.5 in Recurrent Small Cell Lung Cancer - Mayo Clinic

    5 will be assessed by measuring the extent of tumor shrinkage. SC16LD6.5 is an antibody-drug conjugate (ADC). The antibody (SC16) targets a protein that appears ...

  8. Study of Orally Administered AG-120 in Subjects with Advanced Hematologic Malignancies with an IDH1 Mutation - Mayo Clinic

    About this study. The purpose of this Phase I, multicenter study is to evaluate the safety, pharmacokinetics, pharmacodynamics and clinical activity of ...

  9. Study of INTERCEPT Blood System for Red Blood Cells in Regions at Potential Risk for Zika Virus Transfusion-Transmitted Infections (RedeS) - Mayo Clinic

    Stage B: To provide early access to the INTERCEPT pathogen reduction system for RBC in regions where a substantial proportion of the population has been ...

  10. Clinical Study to Evaluate Mavacamten (MYK-461) in Adults With Symptomatic Obstructive Hypertrophic Cardiomyopathy

    This is a multicenter, international, double-blind study of the administration of mavacamten in participants with symptomatic obstructive HCM (oHCM).