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  1. Testing the Addition of Stereotactic Radiation Therapy With Immune Therapy for the Treatment of Patients With Unresectable or Metastatic Renal Cell Cancer, SAMURAI Study - Mayo Clinic

    The purpose of this study is to determine whether the addition of stereotactic ablative radiotherapy (SABR) to the primary tumor in combination with ...

  2. Erismodegib and Lenalidomide After Stem Cell Transplant in Treating Patients With Multiple Myeloma - Mayo Clinic

    Erismodegib and lenalidomide may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth and may delay the recurrence of myeloma ...

  3. A Study to Examine The Effectiveness, Feasibility, and Acceptability of Exercise Intervention on Frailty After Kidney Transplantation. - Mayo Clinic

    The purpose of this study is to conduct a clinical trial examining the preliminary effectiveness, feasibility, and acceptability of an exercise intervention on ...

  4. Cabozantinib-S-Malate Compared With Temozolomide or Dacarbazine in Treating Patients With Melanoma of the Eye - Mayo Clinic

    Cabozantinib-s-malate may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, such as ...

  5. Transcutaneous Delivery Using Syringe and Device-Assisted Methods in Ex-Vivo Human Skin - Mayo Clinic

    The purpose of this study is evaluate the efficacy of transcutaneous delivery of tattoo ink in ex-vivo human skin samples using different methods including ...

  6. A Study of AP160-Complex in Advanced Solid Tumors - Mayo Clinic

    Patients will have tumor biopsies at screening and EOT to evaluate PDL1 expression and TME. Blood samples will be taken for PK and immune response studies. STI- ...

  7. Safety and Efficacy Study of the Medtronic CoreValve® System in the Treatment of Severe, Symptomatic Aortic Stenosis in Intermediate Risk Subjects Who Need Aortic Valve Replacement (SURTAVI). - Mayo Clinic

    Single Arm: The purpose of this trial is to evaluate the safety and effectiveness of transcatheter aortic valve implementation (TAVI) in patients with sever ...

  8. A Study of MT-5111 in HER2-positive Solid Tumors - Mayo Clinic

    About this study. The purpose of this study is to evaluate dose escalation and expansion of MT-5111 (a recombinant fusion protein) in subjects with ...

  9. A Study to Assess the Effectiveness and Safety of Ublituximab in combination with Umbralisib and Venetoclax (U2-V) Compared to Ublituximab and Umbralisib (U2) in Subjects with Chronic Lymphocytic Leukemia (CLL) - Mayo Clinic

    Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and ...

  10. Study of INTERCEPT Blood System for Red Blood Cells in Regions at Potential Risk for Zika Virus Transfusion-Transmitted Infections (RedeS) - Mayo Clinic

    Stage B: To provide early access to the INTERCEPT pathogen reduction system for RBC in regions where a substantial proportion of the population has been ...