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  1. Phase III Open Label First Line Therapy Study of MEDI 4736 (Durvalumab) With or Without Tremelimumab Versus SOC in Non Small-Cell Lung Cancer (NSCLC). - Mayo Clinic

    About this study. This is a randomized, open-label, multi-center, global, Phase III study to determine the efficacy and safety of MEDI4736 + tremelimumab ...

  2. Immune Phenotyping in Amyotrophic Lateral Sclerosis - Mayo Clinic

    About this study. The goals of this study are to identify biomarkers that allow improved staging or prognosis of the disease, and through the discovery of ...

  3. A Study to Validate the Patient-Specific Functional Survey in Patients with Carpal Tunnel Syndrome - Mayo Clinic

    The purpose of this study is to determine if the Patient-Specific Functional Survey (PSFS) is a valid and reliable measure to evaluate functional difficulties ...

  4. RLY-2608-201-Ph2 Study of RLY-2608 in PROS and PIK3CA Driven Malformations - Mayo Clinic

    About this study. The purpose of this study is to compare the efficacy and safety of RLY-2608 versus placebo in adult, adolescent, and pediatric ...

  5. Safety and Efficacy of Selonsertib in Adults With Compensated Cirrhosis Due to Nonalcoholic Steatohepatitis (NASH) - Mayo Clinic

    The primary objective of this study is to evaluate whether selonsertib (SEL; GS-4997) can cause fibrosis regression and reduce associated complications in ...

  6. A Study to Assess the Safety, Tolerability and Effectiveness of LJN452 for Treating Patients who have Primary Biliary Cholangitis - Mayo Clinic

    The purpose of this study is to assess the safety, tolerability and effectiveness of LJN452 for the treatment of patients who have primary biliary cholangitis.

  7. A Study to Evaluate the Long-Term Safety and Effectiveness of Ubenimex in Patients with Pulmonary Arterial Hypertension - Mayo Clinic

    Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and ...

  8. A Study to Evaluate Single DNA Molecule Optical Imaging to Diagnose Facioscapulohumeral Muscular Dystrophy (FSHD) - Mayo Clinic

    The purpose of this study is to evaluate a novel direct single DNA molecule optical imaging system (Bionano) for the FSHD diagnosis. Participation eligibility.

  9. A Study of Defitelio (Defibrotide) for the Prevention of Acute Graft-versus-Host-Disease (AGvHD) - Mayo Clinic

    The purpose of this study is to compare the defibrotide prophylaxis arm vs. standard of care arm for the prevention of aGvHD. Participation eligibility.

  10. Clinical trials - Hematology

    Hematology — Learn about innovative diagnosis and treatment options for blood diseases, including cancers, at Mayo Clinic.