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  1. A Study to Evaluate the Combination of Binimetinib and Palbociclib in Treating Patients with KRAS and NRAS Mutant Metastatic or Unresectable Colorectal Cancer - Mayo Clinic

    Binimetinib and palbociclib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, such as TAS- ...

  2. Remote Blood Biomarker Monitoring in Frontotemporal Lobar Degeneration - Mayo Clinic

    The purpose of this study is to collect and analyze blood specimens from individuals carrying known familial frontotemporal lobar degeneration (f-FTLD) ...

  3. Early Feasibility Study of HyperQureTM RDN System, Laparoscopic Renal Denervation Therapy, in Patients With Resistant Hypertension - Mayo Clinic

    Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and ...

  4. A Study to Evaluate Posoleucel ALVR105 to Treat Kidney Transplant Recipients with BK Viremia - Mayo Clinic

    The key secondary objective is to test the hypothesis that the administration of posoleucel ALVR105 to kidney transplant recipients with BK viremia will ...

  5. Cardiovascular Outcomes Assessment of the MitraClip Therapy Percutaneous Therapy for High Surgical Risk Patients - Mayo Clinic

    Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and ...

  6. A Study of Outcomes after Early Closure of Diverting Loop Ileostomy - Mayo Clinic

    Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and ...

  7. Study of INCB053914 in Subjects With Advanced Malignancies - Mayo Clinic

    About this study. This is an open-label, dose-escalation study of the proviral integration site of Moloney murine leukemia virus (PIM) kinase inhibitor ...

  8. A Study of Apalutamide (ARN-509) in Men With Non-Metastatic Castration-Resistant Prostate Cancer - Mayo Clinic

    The purpose of this study is to evaluate the efficacy and safety of apalutamide in adult men with high-risk non-metastatic castration-resistant prostate cancer.

  9. Avatrombopag for the Treatment of Thrombocytopenia in Adults Scheduled for a Surgical Procedure - Mayo Clinic

    About this study. Phase 3b open-label, multicenter study to evaluate the safety and efficacy of avatrombopag in subjects with thrombocytopenia scheduled for ...

  10. Study to Validate Auto Registry and Integration of Ultrasound into Procedure - Mayo Clinic

    The purpose of this study is to compare the accuracy of the Auto Registration capability on the EPIQ/PercuNav system against existing manual registration ...