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  1. Phase 1/2 Dose Escalation and Efficacy Study of Anti-CD38 Monoclonal Antibody in Patients With Selected CD38+ Hematological Malignancies - Mayo Clinic

    About this study. Primary Objective: Phase 1: To determine the maximum tolerated dose (MTD)/maximum administered dose (MAD) of SAR650984 (Isatuximab).

  2. DNA, Blood, and Skin Cell Repository for Research on ALS and Related Neurodegenerative Disorders at Mayo Clinic Florida

    About this study. This study is intended to obtain clinical information and establish a repository of DNA, RNA, peripheral blood monocyte, lymphocyte and ...

  3. A Study to Evaluate Topical VT30 to Treat Patients with Venous/Lymphatic Malformations Associated with PIK3CA or TEK Gene Mutations - Mayo Clinic

    Part 2 is a 12-week treatment, randomized, placebo-controlled, double-blind, safety and exploratory effectiveness study. Part 2 will be initiated only after the ...

  4. Developing Novel Microbiota-Targeted Therapies for Irritable Bowel Syndrome - Mayo Clinic

    This longitudinal study is being done to understand mechanisms underlying development of irritable bowel syndrome (IBS) and the role of the gut bacteria in ...

  5. Exercise Preconditioning and Breast Cancer Cardiotoxicity - Mayo Clinic

    About this study. The purpose of this study is to determine whether a supervised exercise-training program, initiated prior to chemotherapy induction ...

  6. A Study of the Structural Parts of Bone in Related Diseases that Have Increased Risk of Fractures - Mayo Clinic

    Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and ...

  7. A Study Of Oral CP-690,550 As A Maintenance Therapy For Ulcerative Colitis - Mayo Clinic

    The study proposes to assess whether compared to placebo, CP-690,550 is effective, safe, and tolerable maintenance therapy in subjects with Ulcerative Colitis ( ...

  8. A Study of Massage Therapy Alone and in Combination with Acupuncture for Breast Cancer Patients Undergoing Autologous Tissue Reconstruction - Mayo Clinic

    The purpose of this study is to explore the effectiveness of massage therapy combined with acupuncture in breast cancer patients recovering from autologous ...

  9. Inotropes: Intent and Result of Elective Initiation During Heart Failure Hospitalization - Mayo Clinic

    About this study. The purpose of this study is to identify clinical demographics of patients initiated on inotropes during a heart failure admission and ...

  10. Simtuzumab (GS-6624) in the Treatment of Cirrhosis Due to NASH - Mayo Clinic

    This study is to evaluate the safety and efficacy of simtuzumab (GS-6624) in adults with compensated cirrhosis due to Non-Alcoholic Steatohepatitis (NASH). It ...