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  1. A Study to Evaluate Gemcitabine and MK-3475 (Pembrolizumab) to Treat Patients with BCG-Unresponsive Non-Muscle Invasive Bladder Cancer - Mayo Clinic

    The purpose of this study is to assess the effect of adding pembrolizumab to gemcitabine in treating patients with non-muscle invasive bladder cancer whose ...

  2. A Study of Avelumab With Axitinib Versus Sunitinib In Advanced Renal Cell Cancer (JAVELIN Renal 101) - Mayo Clinic

    About this study. This is a phase 3 randomized trial evaluating the anti-tumor activity and safety of avelumab in combination with axitinib and of sunitinib ...

  3. A Phase 1b/2 Safety and Tolerability of MEDI6469 in Combination With Therapeutic Immune Agents or Monoclonal Antibodies - Mayo Clinic

    Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and ...

  4. Phase I Safety and Feasibility Study of Intracoronary Delivery of Autologous Bone Marrow Derived Mononuclear Cells - Mayo Clinic

    This procedure has the potential to foster a new strategy for congenital heart patients. This is an open-label study of autologous MNC derived from bone marrow ...

  5. The Effects of Glucagon on Hepatic Metabolism - Mayo Clinic

    About this study. The purpose of this study is to measure hepatic extraction of amino acid (AA) in response to physiologic post-prandial concentrations of ...

  6. A Study to Evaluate the Effect of Olorinab on Gastrointestinal Transit in Patients with Irritable Bowel Syndrome - Mayo Clinic

    The purpose of this study is to evaluate gastric, small-bowel, and colonic transit in subjects with IBS-C and IBS-D treated with multiple (three times daily) ...

  7. Molecular Profiling of Tumors From Cancer Patients Who Are Exceptional Responders - Mayo Clinic

    Eligibility: - People who are documented exceptional responders to cancer treatment. They must have given a tumor sample that is available to researchers.

  8. Safety & Efficacy of Intramyocardial Injection of Mesenchymal Precursor Cells on Myocardial Function in LVAD Recipients - Mayo Clinic

    The main purpose of this research is to determine whether injecting mesenchymal precursor cells (MPC) into the heart during surgery to implant a left ...

  9. Body Fat Analysis in Professional Women’s Basketball Athletes - Mayo Clinic

    The purpose of this study is to determine how participation in women's professional basketball impacts body fat and thigh muscle fat composition. Participation ...

  10. A Study to Compare Non-invasive Near-infrared Spectroscopy (NIRS) to Invasive Licox Intracranial Pressure Monitoring in Neurocritical Care - Mayo Clinic

    A Study to Compare Non-invasive Near-infrared Spectroscopy (NIRS) to Invasive Licox Intracranial Pressure Monitoring in Neurocritical Care · Overview.